期刊
FERROELECTRICS
卷 548, 期 1, 页码 133-142出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/00150193.2019.1592520
关键词
HMSN; carbon quantum dots; photothermal effect; fluorescent probe
资金
- National Natural Science Foundation of China [21675091, 21574072, 21874078]
- Taishan Young Scholar Program of Shandong Province [tsqn20161027]
- Major Science and Technology Innovation Project of Shandong Province [2018CXGC1407]
- Key Research and Development Project of Shandong Province [2016GGX102028, 2016GGX102039, 2017GGX20111]
- Project of Shandong Province Higher Educational Science and Technology Program [J15LC20]
- People's Livelihood Science and Technology Project of Qingdao [166257nsh, 173378nsh]
- Innovation Leader Project of Qingdao [168325zhc]
- Postdoctoral Scientific Research Foundation of Qingdao
- First Class Discipline Project of Shandong Province
Hollow mesoporous silica and carbon quantum dots play an important role in the field of biological applications. In this study, a nano-scale hollow mesoporous silica nanosphere (HMSN) was used as the main body of a drug transport system, which filled with a small amount of carbon quantum dots. The hollow mesoporous silica structure provides a large specific surface area and cavity structure for efficient drug loading. And the carbon quantum dots could provide good fluorescence for imaging. By filling carbon quantum dots inside of silica nanospheres and in mesopores on the surface, the hollow mesoporous silica nanospheres became fluorescent and could be used as a fluorescent probe. And the potential photothermal effect of the internal carbon quantum dots also makes it possible to achieve controlled drug release through temperature changes.
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