相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Ixazomib: an investigational drug for the treatment of lymphoproliferative disorders
Piotr Smolewski et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2019)
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition
Susan Wyllie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Identification of Novel Trypanosoma cruzi Proteasome Inhibitors Using a Luminescence-Based High-Throughput Screening Assay
Filip Zmuda et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2019)
Design and Evaluation of Highly Selective Human Immunoproteasome Inhibitors Reveal a Compensatory Process That Preserves Immune Cell Viability
Ena Ladi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors
Wenhu Zhan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study
William L. Hamilton et al.
LANCET INFECTIOUS DISEASES (2019)
Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study
Rob W. van der Pluijm et al.
LANCET INFECTIOUS DISEASES (2019)
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents
Barbara H. Stokes et al.
PLOS PATHOGENS (2019)
The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis
Stanley C. Xie et al.
NATURE MICROBIOLOGY (2019)
Drug Discovery for Kinetoplastid Diseases: Future Directions
Srinivasa P. S. Rao et al.
ACS INFECTIOUS DISEASES (2019)
New proteasome inhibitors in the treatment of multiple myeloma
Vania Tietsche de Moraes Hungria et al.
HEMATOLOGY TRANSFUSION AND CELL THERAPY (2019)
Burden, pathology, and costs of malaria in pregnancy: new developments for an old problem
Stephen J. Rogerson et al.
LANCET INFECTIOUS DISEASES (2018)
Multicenter double-blind randomized controlled trial to evaluate the effectiveness and safety of bortezomib as a treatment for refractory systemic lupus erythematosus
Tomonori Ishii et al.
MODERN RHEUMATOLOGY (2018)
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance
Laura A. Kirkman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis
Min Zhang et al.
SCIENCE (2018)
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
Annie N. Cowell et al.
SCIENCE (2018)
Structural absorption by barbule microstructures of super black bird of paradise feathers
Dakota E. McCoy et al.
NATURE COMMUNICATIONS (2018)
Recent Development of Visceral Leishmaniasis Treatments: Successes, Pitfalls, and Perspectives
Fabiana Alves et al.
CLINICAL MICROBIOLOGY REVIEWS (2018)
Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors
Euna Yoo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome
Jessica L. Bridgford et al.
NATURE COMMUNICATIONS (2018)
Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating
Markus R. Eisele et al.
CELL REPORTS (2018)
Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome
Stanley C. Xie et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Vaccines against malaria-still a long way to go
Kai Matuschewski
FEBS JOURNAL (2017)
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity
Gregory M. LaMonte et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
New developments in anti-malarial target candidate and product profiles
Jeremy N. Burrows et al.
MALARIA JOURNAL (2017)
Proteasome inhibitors in cancer therapy
Elisabet E. Manasanch et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
Protein Degradation Systems as Antimalarial Therapeutic Targets
Caroline L. Ng et al.
TRENDS IN PARASITOLOGY (2017)
A thiol probe for measuring unfolded protein load and proteostasis in cells
Moore Z. Chen et al.
NATURE COMMUNICATIONS (2017)
Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting
Aaron Ciechanover
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY (2017)
A Brief Review of Drug Discovery Research for Human African Trypanosomiasis
Danica R. Cullen et al.
CURRENT MEDICINAL CHEMISTRY (2017)
Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance
Gustavo C. Cerqueira et al.
GENOME BIOLOGY (2017)
Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study
Chanaki Amaratunga et al.
LANCET INFECTIOUS DISEASES (2016)
Structure- and function-based design of Plasmodium-selective proteasome inhibitors
Hao Li et al.
NATURE (2016)
Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness
Shilpi Khare et al.
NATURE (2016)
The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design
Jil Schrader et al.
SCIENCE (2016)
The Future of the RTS, S/AS01 Malaria Vaccine: An Alternative Development Plan
Roly Gosling et al.
PLOS MEDICINE (2016)
Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies
Peter J. Hotez et al.
PLOS NEGLECTED TROPICAL DISEASES (2016)
Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial
H. Tinto et al.
LANCET (2015)
Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study
Michele D. Spring et al.
LANCET INFECTIOUS DISEASES (2015)
Overcoming neglect of kinetoplastid diseases
Graeme Bilbe
SCIENCE (2015)
Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib
Wayne Harshbarger et al.
STRUCTURE (2015)
Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum
Jigang Wang et al.
NATURE COMMUNICATIONS (2015)
Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance
Con Dogovski et al.
PLOS BIOLOGY (2015)
Directional Selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu Loci of Plasmodium falciparum in Kenyan Children Treated With ACT
Gisela Henriques et al.
JOURNAL OF INFECTIOUS DISEASES (2014)
Identification of Potent and Selective Non-covalent Inhibitors of the Plasmodium falciparum Proteasome
Hao Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: an open-label phase 1/2 study
Shaji K. Kumar et al.
LANCET ONCOLOGY (2014)
Broad-Spectrum Antimalarial Activity of Peptido Sulfonyl Fluorides, a New Class of Proteasome Inhibitors
Serena Tschan et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Using Genetic Methods To Define the Targets of Compounds with Antimalarial Activity
Erika L. Flannery et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites
Paul P. Geurink et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Designing the next generation of medicines for malaria control and eradication
Jeremy N. Burrows et al.
MALARIA JOURNAL (2013)
Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity
Eva M. Huber et al.
CELL (2012)
Validation of the Proteasome as a Therapeutic Target in Plasmodium Using an Epoxyketone Inhibitor with Parasite-Specific Toxicity
Hao Li et al.
CHEMISTRY & BIOLOGY (2012)
Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Alexei F. Kisselev et al.
CHEMISTRY & BIOLOGY (2012)
Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells
N. E. Franke et al.
LEUKEMIA (2012)
A framework for assessing the risk of resistance for anti-malarials in development
Xavier C. Ding et al.
MALARIA JOURNAL (2012)
Should I Get Screened for Sleeping Sickness? A Qualitative Study in Kasai Province, Democratic Republic of Congo
Alain Mpanya et al.
PLOS NEGLECTED TROPICAL DISEASES (2012)
Specific Cell-Permeable Inhibitor of Proteasome Trypsin-like Sites Selectively Sensitizes Myeloma Cells to Bortezomib and Carfilzomib
Anne C. Mirabella et al.
CHEMISTRY & BIOLOGY (2011)
Evaluation of the Proteasome Inhibitor MLN9708 in Preclinical Models of Human Cancer
Erik Kupperman et al.
CANCER RESEARCH (2010)
Selective Inhibitor of Proteasome's Caspase-like Sites Sensitizes Cells to Specific Inhibition of Chymotrypsin-like Sites
Matthew Britton et al.
CHEMISTRY & BIOLOGY (2009)
Molecular basis of bortezomib resistance:: proteasome subunit β5 (PSMB5) gene mutation and overexpression of PSMB5 protein
Ruud Oerlemans et al.
BLOOD (2008)
Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon
Andrea Kreidenweiss et al.
MALARIA JOURNAL (2008)
Evidence of Artemisinin-Resistant Malaria in Western Cambodia
Harald Noedl et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites
Paul Hunt et al.
MOLECULAR MICROBIOLOGY (2007)
Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome
Susan D. Demo et al.
CANCER RESEARCH (2007)
20S proteasome and its inhibitors: Crystallographic knowledge for drug development
Ljudmila Borissenko et al.
CHEMICAL REVIEWS (2007)
Evolution and pathology in Chagas disease - A review
Antonio R. L. Teixeira et al.
MEMORIAS DO INSTITUTO OSWALDO CRUZ (2006)
Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome
M Groll et al.
STRUCTURE (2006)
Molecular machines for protein degradation
M Groll et al.
CHEMBIOCHEM (2005)
Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions
K Becker et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2004)
Cell-mediated immune response in megacolon from patients with chronic Chagas' disease
CEP Corbett et al.
DISEASES OF THE COLON & RECTUM (2001)
The IκB kinase (IKK) and NF-κB:: key elements of proinflammatory signalling
M Karin et al.
SEMINARS IN IMMUNOLOGY (2000)