期刊
EUROPEAN JOURNAL OF OPHTHALMOLOGY
卷 30, 期 6, 页码 1440-1447出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/1120672119885045
关键词
Anti-vascular endothelial growth factor; intravitreal drugs; indicator; health records; treatment; retina; appropriate treatment intensity
Purpose: We aimed to develop indicators based on electronic administrative data to compare treatment intensity at a hospital level in Tuscany, Italy. Methods: Data from 3 university hospitals (UHs), 11 local hospitals (LHs) and 2 private hospitals were analysed. Patients newly treated with an intravitreal injection were followed up for 365 days. Indicator #1 concerned hospitals with >80% of injections linked to a drug and patients with all injections linked to a drug. Indicator #2 included patients who received > 3 injections during the first 90 days, regardless of injection-drug linkage. Results: Indicator #1 was computed on four hospitals and included 3210 patients (48.3%). The average number of injections was 3.24 in the largest UH1. Compared to the latter, indicator #1 was significantly lower in UH2 and UH3 (-0.47 and -0.58, respectively; p < 0.001). Indicator #2 was computed on all hospitals and included 2789 patients (41.9%). UH1 delivered about 4.33 injections. Compared to the latter, LH4 delivered +0.62 injections (p < 0.001) and nine other hospitals delivered between -0.22 and -0.94 injections (p < 0.05). Conclusion: The two indicators proved to have the potential for supporting clinicians and policy makers in promoting the appropriate treatment intensity with intravitreal anti-vascular endothelial growth factor drugs.
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