期刊
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
卷 57, 期 3, 页码 428-437出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/ejcts/ezz279
关键词
Non-intubated video-assisted thoracoscopic surgery; Spontaneous ventilation; Perioperative outcomes; Meta-analysis
资金
- National Key R&D Program of China [2016YFC0905400]
- China National Science Foundation [81871893, 81501996]
- Key Project of Guangzhou Scientific Research Project [201804020030]
- High-level university construction project of Guangzhou Medical University [20182737, 201721007, 201715907, 2017160107]
- IVATS National key RD Program [2017YFC0907903, 2017YFC0112704]
- Application, industrialization and generalization of surgical incision protector [2011B090400589]
It remains unclear whether non-intubated video-assisted thoracoscopic surgery (VATS) is comparable or advantageous compared with conventional intubated VATS. Thus, we systematically assessed the feasibility and safety of non-intubated VATS compared with intubated VATS perioperatively for the treatment of different thoracic diseases. An extensive search of literature databases was conducted. Perioperative outcomes were compared between 2 types of operations. The time trend of the overall results was evaluated through a cumulative meta-analysis. Subgroup analyses of different thoracic diseases and study types were examined. Twenty-seven studies including 2537 patients were included in the analysis. A total of 1283 patients underwent non-intubated VATS; intubated VATS was performed on the other 1254 patients. Overall, the non-intubated VATS group had fewer postoperative overall complications [odds ratios (OR) 0.505; P<0.001]; shorter postoperative fasting times [standardized mean difference (SMD) -2.653; P<0.001]; shorter hospital stays (SMD -0.581; P<0.001); shorter operative times (SMD -0.174; P=0.041); shorter anaesthesia times (SMD -0.710; P<0.001) and a lower mortality rate (OR 0.123; P=0.020). Non-intubated VATS may be a safe and feasible alternative to intubated VATS and provide a more rapid postoperative rehabilitation time than conventional intubated VATS.
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