期刊
ENVIRONMENT INTERNATIONAL
卷 131, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.envint.2019.104927
关键词
Air pollution; Depressive symptoms; Anxiety symptoms; Aggressive symptoms; children's mental health
资金
- European Community [211250]
- Netherlands Organization for Health Research and Development
- Sarphati Amsterdam
- Amsterdam UMC
- Erasmus MC, Rotterdam
- Erasmus University Rotterdam
- Netherlands Organization for Health Research and Development (ZonMw)
- Netherlands Organization for Scientific Research (NWO)
- Ministry of Health, Welfare and Sport
- Netherlands Ministry of Infrastructure and the Environment
- European Union [633595, 733206]
- Netherlands Organization for Health Research and Development (NWO) [016.VICI.170.200]
- Federal Ministry for Education, Science, Research and Technology
- Helmholtz Zentrum Munich
- Research Institute at Marien-Hospital Wesel
- LMU Munich
- TU Munich
- IUF Leibniz Research-Institute for Environmental Medicine at the University of Dusseldorf
- Federal Ministry for Environment (IUF Dusseldorf) [FKZ 20462296]
- Commission of the European Communities
- Mead Johnson
- Nestle
- Helmholtz Centre for Environmental Research - UFZ, Leipzig
- Research Institute at Marien-Hospital Wesel, Pediatric Practice, Bad Honnef
- Research Institute at Marien - Hospital Wesel, Pediatric Practice, Bad Honnef
- IUF - Leibniz-Research Institute for Environmental Medicine at the University of Dusseldorf
- National Science Centre, Poland [DEC-2014/15/B/NZ7/00998]
- FP7 HEALS [603946]
- Ministry of Science and Higher Education [3068/7.PR/2014/2]
- Fondation de France [00089597]
- Fondation for Medical Research (FRM)
- National Agency for Research (ANR)
- National Institute for Research in Public Health
- French Ministry of Health (DGS)
- French Ministry of Research
- INSERM
- Paris-Sud University
- French National Institute for Population Health Surveillance (InVS)
- French National Institute for Health Education (INPES)
- European Union
- Diabetes National Research Program
- French Association of Diabetic Patients (AFD)
- ANSES
- Mutuelle Generale de l'Education Nationale, France (a complementary health insurance fund) (MGEN)
- French National Agency for food Security
- French-Language Association for the Study of Diabetes and Metabolism (ALFEDIAM)
- Italian Ministry of Health
- Instituto de Salud Carlos III [Red INMA G03/176, CB06/02/0041]
- Instituto de Salud Carlos III (FIS-FEDER) [PI03/1615, PI04/1509, PI04/1112, PI04/1931, PI04/1436, PI04/2018, PI05/1079, PI05/1052, PI06/1213, PI06/0867, PI07/0314, PI07/0252, PI08/1151, PI09/02647, PI09/02311, PS09/00090, PI11/02591, PI11/02038, PI13/02429, PI13/1944, PI13/2032, PI14/00891, PI14/01687, PI16/00118, PI17/00663, PI18/00909]
- Instituto de Salud Carlos III (Miguel Servet-FEDER) [MS13/00054, MS11/00178, MS16/00085, MSII16/00051, CP18/00018]
- Generalitat de Catalunya-CIRIT [1999SGR 00241]
- La Fundacio La Marato de TV3 [090430]
- Generalitat Valenciana [FISABIO-UGP 15230, 15-244, 15-249]
- Fundacion Alicia Koplowitz
- Department of Health of the Basque Government [2005111093, 2009111069]
- Provincial Government of Gipuzkoa [DFG06/004, DFG08/001]
- Obra Social Cajastur/Fundacion Liberbank
- Universidad de Oviedo
- Consejeria de Salud de la Junta de Andalucia [183/07]
- EU Commission [QLK4-1999-01422, QLK4-2002 00603, CONTAMED FP7-ENV-12502, 282957]
- Fundacion Roger Torne
Background: The association between air pollution exposure and emotional and behavioural problems in children is unclear. We aimed to assess prenatal and postnatal exposure to several air pollutants and child's depressive and anxiety symptoms, and aggressive symptoms in children of 7-11 years. Methods: We analysed data of 13182 children from 8 European population-based birth cohorts. Concentrations of nitrogen dioxide (NO2), nitrogen oxides (NOx), particulate matter (PM) with diameters of <= 10 mu m (PM10), <= 2.5 mu m (PM2.5), and between 10 and 2.5 mu m (PMcoarse), the absorbance of PM2.5 filters (PM(2.5)abs), and polycyclic aromatic hydrocarbons (PAHs) were estimated at residential addresses of each participant. Depressive and anxiety symptoms and aggressive symptoms were assessed at 7-11 years of age using parent reported tests. Children were classified in borderline/clinical range or clinical range using validated cut offs. Region specific models were adjusted for various socio-economic and lifestyle characteristics and then combined using random effect meta-analysis. Multiple imputation and inverse probability weighting methods were applied to correct for potential attrition bias. Results: A total of 1896 (14.4%) children were classified as having depressive and anxiety symptoms in the borderline/clinical range, and 1778 (13.4%) as having aggressive symptoms in the borderline/clinical range. Overall, 1108 (8.4%) and 870 (6.6%) children were classified as having depressive and anxiety symptoms, and aggressive symptoms in the clinical range, respectively. Prenatal exposure to air pollution was not associated with depressive and anxiety symptoms in the borderline/clinical range (e.g. OR 1.02 [95%CI 0.95 to 1.10] per 10 mu g/m(3) higher NO2) nor with aggressive symptoms in the borderline/clinical range (e.g. OR 1.04 [95%CI 0.96 to 1.12] per 10 mu g/m(3) higher NO2). Similar results were observed for the symptoms in the clinical range, and for postnatal exposures to air pollution. Conclusions: Overall, our results suggest that prenatal and postnatal exposure to air pollution is not associated with depressive and anxiety symptoms or aggressive symptoms in children of 7 to 11 years old.
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