期刊
DERMATOLOGIC CLINICS
卷 37, 期 4, 页码 455-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.det.2019.05.007
关键词
Cutaneous T cell lymphoma; Mycosis fungoides; CTCL treatment; Overview; Histology; Clinical correlations
类别
Cutaneous T cell lymphoma (CTCL) represents a heterogeneous group of extranodal non-Hodgkin lymphomas in which monoclonal T lymphocytes infiltrate the skin. The mechanism of CTCL development is not fully understood, but likely involves dysregulation of various genes and signaling pathways. A variety of treatment modalities are available, and although they can induce remission in most patients, the disease may recur after treatment cessation. Owing to relatively low incidence and significant chronicity of disease, and the high morbidity of some therapeutic regimens, further clinical trials are warranted to better define the ideal treatment option for each subtype of CTCL.
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