期刊
CURRENT OPINION IN CELL BIOLOGY
卷 60, 期 -, 页码 139-144出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2019.06.007
关键词
-
类别
资金
- Human Frontiers Science Program [CDA00074/2014]
Cells need to regulate the size and shape of their organelles for proper function. For example, the mitotic spindle adapts its size to changes in cell size over several orders of magnitude, but we lack a mechanistic understanding of how this is achieved. Here, we review our current knowledge of how small and large spindles assemble and ask which microtubule-based biophysical processes (nucleation, polymerization dynamics, transport) may be responsible for spindle size regulation. Finally, we review possible cell-scale mechanisms that put spindle size under the regulation of cell size.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据