期刊
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
卷 20, 期 3, 页码 137-146出版社
CIG MEDIA GROUP, LP
DOI: 10.1016/j.clml.2019.10.006
关键词
F-18-FDG; MALT; Marginal zone lymphoma; PET; PET/CT
Mucosa-associated lymphoid tissue (MALT) lymphoma involves the mucosa-associated lymphoid tissue potentially arising from any mucosal site, with the stomach as the most common site of involvement. MALT lymphoma is not usually an aggressive disease with a good prognosis except for selected cases. Fluorine-18 (F-18) fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is a noninvasive imaging tool used for staging, restaging, and evaluation of the treatment response in non-Hodgkin and Hodgkin lymphoma. However, its effective role in MALT lymphoma is not yet clear. The open question is whether these lymphomas are F-18-FDG avid or not, with conflicting results reported in the literature. Consequently, the possible clinical role of F-18-FDG PET/CT for staging and restaging purposes is under debate. The aim of the present review was to analyze the reported data about the role of F-18-FDG PET or PET/CT in patients with MALT lymphoma. We performed a comprehensive computer literature search of the Scopus, Cochrane, PubMed/MEDLINE, and Embase databases, including articles reported up to August 2019. We included 32 studies that had analyzed F-18-FDG PET or PET/CT for patients with MALT lymphoma. We analyzed the metabolic behavior of MALT lymphoma using F-18-FDG PET and the effect of the PET findings in the staging, treatment response evaluation, and prognosis. (C) 2019 Elsevier Inc. All rights reserved.
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