期刊
BIOLOGICAL PROCEDURES ONLINE
卷 18, 期 -, 页码 -出版社
BMC
DOI: 10.1186/s12575-016-0048-8
关键词
Aqueous two-phase system (ATPS); Biomolecule separation; Solvent extraction; Veterinary drug residues
资金
- Ministry of Agriculture the People's Republic of China [2011BAK10B07-5]
- Risk assessment of quality and safety of livestock and poultry products [GJFP2016008]
- Huazhong Agricultural University, Independent Technology Innovation Fund Projects [2662015PY021]
Aqueous two-phase system (ATPS) is a liquid-liquid fractionation technique and has gained an interest because of great potential for the extraction, separation, purification and enrichment of proteins, membranes, viruses, enzymes, nucleic acids and other biomolecules both in industry and academia. Although, the partition behavior involved in the method is complex and difficult to predict. Current research shows that it has also been successfully used in the detection of veterinary drug residues in food, separation of precious metals, sewage treatment and a variety of other purposes. The ATPS is able to give high recovery yield and is easily to scale up. It is also very economic and environment friendly method. The aim of this review is to overview the basics of ATPS, optimization and its applications.
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