相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Immuno-oncological Efficacy of RXDX-106, a Novel TAM (TYRO3, AXL, MER) Family Small-Molecule Kinase Inhibitor
Yumi Yokoyama et al.
CANCER RESEARCH (2019)
Living on the Edge: Efferocytosis at the Interface of Homeostasis and Pathology
Sho Morioka et al.
IMMUNITY (2019)
MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression
Yao Jiang et al.
NATURE COMMUNICATIONS (2019)
MERTK Acts as a Costimulatory Receptor on Human CD8+ T Cells
Marlies J. W. Peeters et al.
CANCER IMMUNOLOGY RESEARCH (2019)
PD-1 expression on tumor-specific T cells: Friend or foe for immunotherapy?
Sylvain Simon et al.
ONCOIMMUNOLOGY (2018)
Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response
Eric Ubil et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
The small-molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis
B. R. Branchford et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2018)
Targeting Gas6/TAM in cancer cells and tumor microenvironment
Guiling Wu et al.
MOLECULAR CANCER (2018)
MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity
Alisa B. Lee-Sherick et al.
JCI INSIGHT (2018)
UNC2025, a MERTK Small-Molecule Inhibitor, Is Therapeutically Effective Alone and in Combination with Methotrexate in Leukemia Models
Deborah DeRyckere et al.
CLINICAL CANCER RESEARCH (2017)
TAM receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy
Yemsratch T. Akalu et al.
IMMUNOLOGICAL REVIEWS (2017)
Growth Arrest-Specific 6 Enhances the Suppressive Function of CD4+ CD25+ Regulatory T Cells Mainly through Axl Receptor
Guang-ju Zhao et al.
MEDIATORS OF INFLAMMATION (2017)
Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression
Canan Kasikara et al.
MOLECULAR CANCER RESEARCH (2017)
TAM Receptor Tyrosine Kinases in Cancer Drug Resistance
Mikaella Vouri et al.
CANCER RESEARCH (2017)
AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective
Samuel H. Myers et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer
R. B. Birge et al.
CELL DEATH AND DIFFERENTIATION (2016)
The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity
Pamela Y. Chan et al.
SCIENCE (2016)
The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer Therapy
Magdalena Paolino et al.
CANCERS (2016)
TAM Receptor Signaling in Immune Homeostasis
Carla V. Rothlin et al.
ANNUAL REVIEW OF IMMUNOLOGY VOL 33 (2015)
Targeted Axl Inhibition Primes Chronic Lymphocytic Leukemia B Cells to Apoptosis and Shows Synergistic/Additive Effects in Combination with BTK Inhibitors
Sutapa Sinha et al.
CLINICAL CANCER RESEARCH (2015)
MERTK as negative regulator of human T cell activation
Raquel Cabezon et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2015)
The Mertk receptor tyrosine kinase promotes T-B interaction stimulated by IgD B-cell receptor cross-linking
Wen-Hai Shao et al.
JOURNAL OF AUTOIMMUNITY (2014)
Receptor Tyrosine Kinases, TYRO3, AXL, and MER, Demonstrate Distinct Patterns and Complex Regulation of Ligand-induced Activation
Wen-I Tsou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
Magdalena Paolino et al.
NATURE (2014)
Diversification of TAM receptor tyrosine kinase function
Anna Zagorska et al.
NATURE IMMUNOLOGY (2014)
TAM Receptors Support Neural Stem Cell Survival, Proliferation and Neuronal Differentiation
Rui Ji et al.
PLOS ONE (2014)
Increased expression of Mer tyrosine kinase in circulating dendritic cells and monocytes of lupus patients: correlations with plasma interferon activity and steroid therapy
Brendan A. Hilliard et al.
ARTHRITIS RESEARCH & THERAPY (2014)
The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer
Douglas K. Graham et al.
NATURE REVIEWS CANCER (2014)
T Cell-Derived Protein S Engages TAM Receptor Signaling in Dendritic Cells to Control the Magnitude of the Immune Response
Eugenio A. Carrera Silva et al.
IMMUNITY (2013)
Systemic Autoimmunity in TAM Triple Knockout Mice Causes Inflammatory Brain Damage and Cell Death
Qiutang Li et al.
PLOS ONE (2013)
Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer
Lidia Bosurgi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases: implications for therapy
Asish K. Ghosh et al.
BLOOD (2011)
Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization
J. M. E. M. Cosemans et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2010)
The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development
Il-Kyoo Park et al.
BLOOD (2009)
The mer receptor tyrosine kinase is required for the loss of B cell tolerance in the chronic graft-versus-host disease model of systemic lupus erythematosus
Wen-Hai Shao et al.
JOURNAL OF IMMUNOLOGY (2008)
The role of Tyro 3 subfamily receptors in the regulation of hemostasis and megakaryocytopoiesis
Haikun Wang et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2007)
Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells
Heather M. Seitz et al.
JOURNAL OF IMMUNOLOGY (2007)
Lymphoblastic leukemia/lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase
A. K. Keating et al.
ONCOGENE (2006)
TAM receptor function in the retinal pigment epithelium
Dipti Prasad et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2006)
Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases
Anouk Caraux et al.
NATURE IMMUNOLOGY (2006)
Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia
DK Graham et al.
CLINICAL CANCER RESEARCH (2006)
Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses
WR Gould et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2005)
The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity
EM Behrens et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family
QX Lu et al.
SCIENCE (2001)