期刊
BLOOD REVIEWS
卷 40, 期 -, 页码 -出版社
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.blre.2019.100638
关键词
Thrombocytopenia; Pregnancy; Immune thrombocytopenia; Gestational thrombocytopenia; Preeclampsia; Thrombotic thrombocytopenic purpura; von Willebrand disease; Hemolytic uremic syndrome
类别
资金
- 2018 HTRS/Novo Nordisk Clinical Fellowship in Hemophilia and Rare Bleeding Disorders from the Hemostasis and Thrombosis Research Society
- Novo Nordisk, Inc.
Thrombocytopenia during pregnancy presents unique challenges for the hematologist. Obstetricians generally manage many of the pregnancy-specific etiologies, ranging from the benign (gestational thrombocytopenia) to the life-threatening (preeclampsia; hemolysis, elevated liver enzymes and low platelets syndrome; and acute fatty liver of pregnancy). However, hematologists may be consulted for atypical and severe presentations and to help manage non-pregnancy specific etiologies, including immune thrombocytopenia, thrombotic thrombocytopenic purpura, hemolytic uremic syndrome and antiphospholipid syndrome, among others, in which maternal and fetal risks must be considered. This review provides a general approach to the diagnosis and management of thrombocytopenia in pregnancy for the consulting hematologist.
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