相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Expanding the Biologist's Toolkit with CRISPR-Cas9
Samuel H. Sternberg et al.
MOLECULAR CELL (2015)
Genome Editing Technologies: Defining a Path to Clinic
Jacqueline Corrigan-Curay et al.
MOLECULAR THERAPY (2015)
Embryo editing sparks epic debate
David Cyranoski et al.
NATURE (2015)
Don't edit the human germ line
Edward Lanphier et al.
NATURE (2015)
Mapping the precision of genome editing
Richard Gabriel et al.
NATURE BIOTECHNOLOGY (2015)
Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors
Xiaoling Wang et al.
NATURE BIOTECHNOLOGY (2015)
Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
Daesik Kim et al.
NATURE METHODS (2015)
A prudent path forward for genomic engineering and germline gene modification
David Baltimore et al.
SCIENCE (2015)
Genome editing at the crossroads of delivery, specificity, and fidelity
Ignazio Maggio et al.
TRENDS IN BIOTECHNOLOGY (2015)
CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes
Puping Liang et al.
PROTEIN & CELL (2015)
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Shengdar Q. Tsai et al.
NATURE BIOTECHNOLOGY (2015)
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
Richard L. Frock et al.
NATURE BIOTECHNOLOGY (2015)
Creating a monomeric endonuclease TALE-I-SceI with high specificity and low genotoxicity in human cells
Jianfei Lin et al.
NUCLEIC ACIDS RESEARCH (2015)
Genome Engineering with Targetable Nucleases
Dana Carroll
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83 (2014)
What's Changed with Genome Editing?
Shengdar Q. Tsai et al.
CELL STEM CELL (2014)
Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing
Adrian Veres et al.
CELL STEM CELL (2014)
Whole-Genome Sequencing Analysis Reveals High Specificity of CRISPR/Cas9 and TALEN-Based Genome Editing in Human iPSCs
Cory Smith et al.
CELL STEM CELL (2014)
Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease
Carolin Anders et al.
NATURE (2014)
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
Xuebing Wu et al.
NATURE BIOTECHNOLOGY (2014)
Dimeric CRISPR RNA-guided Fokl nucleases for highly specific genome editing
Shengdar Q. Tsai et al.
NATURE BIOTECHNOLOGY (2014)
Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
Cem Kuscu et al.
NATURE BIOTECHNOLOGY (2014)
Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity
John P. Guilinger et al.
NATURE METHODS (2014)
CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences
Yanni Lin et al.
NUCLEIC ACIDS RESEARCH (2014)
Protospacer Adjacent Motif (PAM)-Distal Sequences Engage CRISPR Cas9 DNA Target Cleavage
Regina Cencic et al.
PLOS ONE (2014)
A TAL effector repeat architecture for frameshift binding
Annekatrin Richter et al.
NATURE COMMUNICATIONS (2014)
BurrH: a new modular DNA binding protein for genome engineering
Alexandre Juillerat et al.
SCIENTIFIC REPORTS (2014)
The I-TevI Nuclease and Linker Domains Contribute to the Specificity of Monomeric TALENs
Benjamin P. Kleinstiver et al.
G3-GENES GENOMES GENETICS (2014)
Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?
Mireille Betermier et al.
PLOS GENETICS (2014)
BuD, a helix-loop-helix DNA-binding domain for genome modification
Stefano Stella et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2014)
Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism
Stefano Stella et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2013)
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
Lei S. Qi et al.
CELL (2013)
Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System
Baohui Chen et al.
CELL (2013)
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran et al.
CELL (2013)
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Luke A. Gilbert et al.
CELL (2013)
TALEN-based Gene Correction for Epidermolysis Bullosa
Mark J. Osborn et al.
MOLECULAR THERAPY (2013)
A ligation-independent cloning technique for high-throughput assembly of transcription activator-like effector genes
Jonathan L. Schmid-Burgk et al.
NATURE BIOTECHNOLOGY (2013)
DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
NATURE BIOTECHNOLOGY (2013)
Locus-specific editing of histone modifications at endogenous enhancers
Eric M. Mendenhall et al.
NATURE BIOTECHNOLOGY (2013)
A library of TAL effector nucleases spanning the human genome
Yongsub Kim et al.
NATURE BIOTECHNOLOGY (2013)
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
Vikram Pattanayak et al.
NATURE BIOTECHNOLOGY (2013)
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Yanfang Fu et al.
NATURE BIOTECHNOLOGY (2013)
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
Wenyan Jiang et al.
NATURE BIOTECHNOLOGY (2013)
RNA-guided gene activation by CRISPR-Cas9-based transcription factors
Pablo Perez-Pinera et al.
NATURE METHODS (2013)
CRISPR RNA-guided activation of endogenous human genes
Morgan L. Maeder et al.
NATURE METHODS (2013)
Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells
Maarten Holkers et al.
NUCLEIC ACIDS RESEARCH (2013)
Optimization of scarless human stem cell genome editing
Luhan Yang et al.
NUCLEIC ACIDS RESEARCH (2013)
High Frequency Targeted Mutagenesis Using Engineered Endonucleases and DNA-End Processing Enzymes
Fabien Delacote et al.
PLOS ONE (2013)
TAL Effector Specificity for base 0 of the DNA Target Is Altered in a Complex, Effector- and Assay-Dependent Manner by Substitutions for the Tryptophan in Cryptic Repeat-1
Erin L. Doyle et al.
PLOS ONE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
Compact designer TALENs for efficient genome engineering
Marine Beurdeley et al.
NATURE COMMUNICATIONS (2013)
Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
J. Ross Chapman et al.
MOLECULAR CELL (2012)
FLASH assembly of TALENs for high-throughput genome editing
Deepak Reyon et al.
NATURE BIOTECHNOLOGY (2012)
Chimeric TALE recombinases with programmable DNA sequence specificity
Andrew C. Mercer et al.
NUCLEIC ACIDS RESEARCH (2012)
TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction
Erin L. Doyle et al.
NUCLEIC ACIDS RESEARCH (2012)
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers
Adrian W. Briggs et al.
NUCLEIC ACIDS RESEARCH (2012)
Targeting G with TAL Effectors: A Comparison of Activities of TALENs Constructed with NN and NK Repeat Variable Di-Residues
Michelle L. Christian et al.
PLOS ONE (2012)
Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
Giedrius Gasiunas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target
Amanda Nga-Sze Mak et al.
SCIENCE (2012)
Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors
Dong Deng et al.
SCIENCE (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Genome-wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells
Roberto Chiarle et al.
CELL (2011)
A TALE nuclease architecture for efficient genome editing
Jeffrey C. Miller et al.
NATURE BIOTECHNOLOGY (2011)
An unbiased genome-wide analysis of zinc-finger nuclease specificity
Richard Gabriel et al.
NATURE BIOTECHNOLOGY (2011)
Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection
Vikram Pattanayak et al.
NATURE METHODS (2011)
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Ines G. Munoz et al.
NUCLEIC ACIDS RESEARCH (2011)
TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
Ting Li et al.
NUCLEIC ACIDS RESEARCH (2011)
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
Tomas Cermak et al.
NUCLEIC ACIDS RESEARCH (2011)
The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli
Rimantas Sapranauskas et al.
NUCLEIC ACIDS RESEARCH (2011)
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
Claudio Mussolino et al.
NUCLEIC ACIDS RESEARCH (2011)
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence
Ekaterina Semenova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Homing Endonucleases: From Microbial Genetic Invaders to Reagents for Targeted DNA Modification
Barry L. Stoddard
STRUCTURE (2011)
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
Michael R. Lieber
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)
Xanthomonas AvrBs3 Family-Type III Effectors: Discovery and Function
Jens Boch et al.
ANNUAL REVIEW OF PHYTOPATHOLOGY, VOL 48 (2010)
Targeting DNA Double-Strand Breaks with TAL Effector Nucleases
Michelle Christian et al.
GENETICS (2010)
Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors
Jens Boch et al.
SCIENCE (2009)
A Simple Cipher Governs DNA Recognition by TAL Effectors
Matthew J. Moscou et al.
SCIENCE (2009)
Nucleases and helicases take center stage in homologous recombination
Eleni P. Mimitou et al.
TRENDS IN BIOCHEMICAL SCIENCES (2009)
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases
Pilar Redondo et al.
NATURE (2008)
High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR)
Schmidt Manfred et al.
NATURE METHODS (2007)
Engineered I-Crel derivatives cleaving sequences from the human XPC gene can induce highly efficient gene correction in mammalian cells
Sylvain Arnould et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
FD Urnov et al.
NATURE (2005)
Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements
FJM Mojica et al.
JOURNAL OF MOLECULAR EVOLUTION (2005)
Enhancing gene targeting with designed zinc finger nucleases
M Bibikova et al.
SCIENCE (2003)