期刊
BIOELECTROMAGNETICS
卷 38, 期 1, 页码 53-62出版社
WILEY
DOI: 10.1002/bem.22014
关键词
cold atmospheric plasma; cancer; static magnetic field; plasma efficacy; cold plasma selectivity
资金
- National Science Foundation [1465061]
- Division Of Physics
- Direct For Mathematical & Physical Scien [1465061] Funding Source: National Science Foundation
It has been reported since late 1970 that magnetic field interacts strongly with biological systems. Cold atmospheric plasma (CAP) has also been widely studied over the past few decades in physics, biology, and medicine. In this study, we propose a novel idea to combine static magnetic field (SMF) with CAP as a tool for cancer therapy. Breast cancer cells and wild type fibroblasts were cultured in 96-well plates and treated by CAP with or without SMF. Breast cancer cells MDA-MB-231 showed a significant decrease in viability after direct plasma treatment with SMF (compared to only plasma treatment). In addition, cancer cells treated by the CAP-SMF-activated medium (indirect treatment) also showed viability decrease but was slightly weaker than the direct plasma-SMF treatment. By integrating the use of SMF and CAP, we were able to discover their advantages that have yet to be utilized. Bioelectromagnetics. 38:53-62, 2017. (c) 2016 Wiley Periodicals, Inc.
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