期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 64, 期 2, 页码 -出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01885-19
关键词
Staphylococcus aureus; MRSA; exebacase; CF-301; lysin; synergy; direct lytic agent
In vitro synergy between an antimicrobial protein lysin (cell wall hydrolase) called exebacase and each of 12 different antibiotics was examined against Staphylococcus aureus isolates using a nonstandard medium approved for exebacase susceptibility testing by the Clinical and Laboratory Standards Institute. In the check-erboard assay format, fractional inhibitory concentration index values of <= 0.5, consistent with synergy, were observed for the majority of interactions tested. Synergy was further confirmed in time-kill assays.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据