期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 59, 期 8, 页码 3063-3068出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201913023
关键词
green chemistry; O-dealkylation; C-dealkylation; renewable resources; bond cleavage
资金
- Research Foundation Flanders (FWO) (WOG)
- Research Foundation Flanders (FWO) (BioFact Excellence of Science project) [30902231]
- UAntwerp (BOF)
- Research Board of UGent
- VLAIO/Catalisti (ARBOREF)
- BIO-HarT project
- Hercules
- Francqui Foundation
- FWO
An efficient conversion of biorenewable ferulic acid into bio-catechol has been developed. The transformation comprises two consecutive defunctionalizations of the substrate, that is, C-O (demethylation) and C-C (de-2-carboxyvinylation) bond cleavage, occurring in one step. The process only requires heating of ferulic acid with HCl (or H2SO4) as catalyst in pressurized hot water (250 degrees C, 50 bar N-2). The versatility is shown on a variety of other (biorenewable) substrates yielding up to 84% di-(catechol, resorcinol, hydroquinone) and trihydroxybenzenes (pyrogallol, hydroxyquinol), in most cases just requiring simple extraction as work-up.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据