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Alex D. Michaels et al.
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Gregg L. Semenza
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Volker H. Haase
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Elizabeth C. Nowak et al.
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J. D. Wolchok et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
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Tianchi Yu et al.
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Marica Garziera et al.
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Combination cancer immunotherapies tailored to the tumour microenvironment
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Non-classical HLA-class I expression in serous ovarian carcinoma: Correlation with the HLA-genotype, tumor infiltrating immune cells and prognosis
Emilia Andersson et al.
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Sofia Farkona et al.
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Yosra Messai et al.
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CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer
Kipp Weiskopf et al.
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Mun Chiang Chan et al.
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Immune-checkpoint blockade - durable cancer control
Elizabeth I. Buchbinder et al.
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Caroline Wigerup et al.
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Stephanie C. Casey et al.
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Hui Li et al.
TUMOR BIOLOGY (2016)
Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2
Layale Yaghi et al.
ONCOTARGET (2016)
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AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2015)
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Eric F. Zhu et al.
CANCER CELL (2015)
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Suzanne L. Topalian et al.
CANCER CELL (2015)
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Mitesh J. Borad et al.
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Michael A. Postow et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
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Xiaojuan Liu et al.
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Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma
R. J. Motzer et al.
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Huimin Zhang et al.
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Padmanee Sharma et al.
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Meriem Hasmim et al.
FRONTIERS IN IMMUNOLOGY (2015)
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Edgardo D. Carosella et al.
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Autophagic degradation of GZMB/granzyme B
Elodie Viry et al.
AUTOPHAGY (2014)
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Ivraym B. Barsoum et al.
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David R. Soto-Pantoja et al.
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Tumor Plasticity Interferes with Anti-Tumor Immunity
Salem Chouaib et al.
CRITICAL REVIEWS IN IMMUNOLOGY (2014)
Challenges and developing solutions for increasing the benefits of IL-2 treatment in tumor therapy
Denise Skrombolas et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2014)
Hypoxia-inducible factors in regulation of immune responses in tumour microenvironment
Vinit Kumar et al.
IMMUNOLOGY (2014)
Phase II Study of the Safety and Antitumor Activity of the Hypoxia-Activated Prodrug TH-302 in Combination With Doxorubicin in Patients With Advanced Soft Tissue Sarcoma
Sant P. Chawla et al.
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PD-L1 is a novel direct target of HIF-1α., and its blockade under hypoxia enhanced MDSC-mediated T cell activation
Muhammad Zaeem Noman et al.
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The Histone Deacetylase Inhibitor, Vorinostat, Represses Hypoxia Inducible Factor 1 Alpha Expression through Translational Inhibition
Darren M. Hutt et al.
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G. Amodio et al.
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Muhammad Zaeem Noman et al.
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Giuseppe Curigliano et al.
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Meriem Hasmim et al.
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Jedd D. Wolchok et al.
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Joanna Baginska et al.
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Zachary A. Cooper et al.
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Naoko Yamada et al.
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Stephen B. Willingham et al.
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Gregg L. Semenza
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
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Wei-Hua Yan
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Salem Chouaib et al.
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Wolf Herman Fridman et al.
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Jessica E. S. Bohonowych et al.
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Mark P. Chao et al.
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Muhammad Zaeem Noman et al.
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Meriem Hasmim et al.
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Leos Kren et al.
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William R. Wilson et al.
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SaeGwang Park et al.
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Erika Terzuoli et al.
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Nathalie M. Mazure et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
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Victoria Moreno-Manzano et al.
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Siddhartha Jaiswal et al.
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Ravindra Majeti et al.
CELL (2009)
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Kristina M. Cook et al.
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Development of HIF-1 inhibitors for cancer therapy
Barbara Onnis et al.
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Gregory Bellot et al.
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KangAe Lee et al.
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Edgardo D. Carosella et al.
BLOOD (2008)
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D. Robert Siemens et al.
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Mei Y. Koh et al.
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The tumor microenvironment and its role in promoting tumor growth
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Inhibitory B7-family molecules in the tumour microenvironment
Weiping Zou et al.
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Drug resistance and the solid tumor microenvironment
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Adoptive T cell therapy for cancer in the clinic
Carl H. June
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Gael Mouillot et al.
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GV Thomas et al.
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PK Majumder et al.
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A Rapisarda et al.
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AM Shannon et al.
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NJ Mabjeesh et al.
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AL Harris
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Induction of HIF-1α in response to hypoxia is instantaneous
UR Jewell et al.
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