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An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N-nitrosourea-mutagenized mouse embryonic stem cells
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Age-related changes in cartilage endogenous osteogenic protein-1 (OP-1)
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Down-regulation of human type II collagen gene expression by transforming growth factor-β1 (TGF-β1) in articular chondrocytes involves SP3/SP1 ratio
C Chadjichristos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Immunohistochemical localization of osteogenetic protein (OP-1) and its receptors in rabbit articular cartilage
C Muehleman et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2002)
Cartilage-derived morphogenetic protein-1 and-2 are endogenously expressed in healthy and osteoarthritic human articular chondrocytes and stimulate matrix synthesis
K Bobacz et al.
OSTEOARTHRITIS AND CARTILAGE (2002)
Aging, articular cartilage chondrocyte senescence and osteoarthritis
JA Martin et al.
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Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion
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Activation of latent transforming growth factor β1 by stromelysin 1 in extracts of growth plate Chondrocyte-derived matrix vesicles
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Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-β-induced aggrecangene expression in chondrogenic ATDC5 cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
TGF-β/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage
X Yang et al.
JOURNAL OF CELL BIOLOGY (2001)
Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice
S Takeda et al.
GENES & DEVELOPMENT (2001)
Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins
ZA Quinn et al.
NUCLEIC ACIDS RESEARCH (2001)
Inhibition of E-selectin gene expression by transforming growth factor β in endothelial cells involves coactivator integration of Smad and nuclear factor κB-mediated signals
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JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Age-related effects of TGF-β on proteoglycan synthesis in equine articular cartilage
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Cbfa1 is a positive regulatory factor in chondrocyte maturation
H Enomoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Human articular chondrocytes express osteogenic protein-1
S Chubinskaya et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2000)
Characterization of a bone morphogenetic protein-responsive Smad-binding element
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Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections
HM van Beuningen et al.
OSTEOARTHRITIS AND CARTILAGE (2000)
Dexamethasone inhibition of TGF beta-induced cell growth and type II collagen mRNA expression through ERK-integrated AP-1 activity in cultured rat articular chondrocytes
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OSTEOARTHRITIS AND CARTILAGE (2000)
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