相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Recent Progress in Histone Deacetylase Inhibitors as Anticancer Agents
Loredana Cappellacci et al.
CURRENT MEDICINAL CHEMISTRY (2020)
Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models
Yves Depetter et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Cancer statistics, 2019
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2019)
LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells
Rhys G. Morgan et al.
HAEMATOLOGICA (2019)
Targeting nuclear β-catenin as therapy for post-myeloproliferative neoplasm secondary AML
Dyana T. Saenz et al.
LEUKEMIA (2019)
Integrative regulation of physiology by histone deacetylase 3
Matthew J. Emmett et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Human Platelet Lysate as Validated Replacement for Animal Serum to Assess Chemosensitivity
Miriam Pons et al.
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION (2019)
WT1 protein is cleaved by caspase-3 in apoptotic leukemic cells
Jichen Ruan et al.
LEUKEMIA & LYMPHOMA (2018)
Senescence-associated reprogramming promotes cancer stemness
Maja Milanovic et al.
NATURE (2018)
Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells
Miriam Pons et al.
ARCHIVES OF TOXICOLOGY (2018)
The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines
Fiona R. Kolbinger et al.
ARCHIVES OF TOXICOLOGY (2018)
Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors
Andreas Sellmer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Targeting HDAC3 Activity with RGFP966 Protects Against Retinal Ganglion Cell Nuclear Atrophy and Apoptosis After Optic Nerve Injury
Heather M. Schmitt et al.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2018)
HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130
Anja Goeder et al.
NATURE COMMUNICATIONS (2018)
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells
Katrin Noack et al.
ARCHIVES OF TOXICOLOGY (2017)
c-Myc Modulation and Acetylation Is a Key HDAC Inhibitor Target in Cancer
Angela Nebbioso et al.
CLINICAL CANCER RESEARCH (2017)
HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer
N. Stojanovic et al.
ONCOGENE (2017)
Targeting breast cancer stem cells by novel HDAC3-selective inhibitors
Hao-Yu Hsieh et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Targeting HDAC3, a new partner protein of AKT in the reversal of chemoresistance in acute myeloid leukemia via DNA damage response
J. Long et al.
LEUKEMIA (2017)
Interstrand Crosslink Repair as a Target for HDAC Inhibition
Teodora Nikolova et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2017)
The CUG-translated WT1, not AUG-WT1, is an oncogene
Kun Yeong Lee et al.
CARCINOGENESIS (2017)
Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase
Idris Raji et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
Stem Cell Guardians - Old and New Perspectives in LSC Biology
Gillian A. Horne et al.
CURRENT DRUG TARGETS (2017)
Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemia
Raajit Rampal et al.
HAEMATOLOGICA (2016)
Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemia
Raajit Rampal et al.
HAEMATOLOGICA (2016)
Small-molecule inhibitors of the Myc oncoprotein
Steven Fletcher et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2015)
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies
Geoffrey M. Matthews et al.
BLOOD (2015)
HDAC8 Inhibition Specifically Targets Inv(16) Acute Myeloid Leukemic Stem Cells by Restoring p53 Acetylation
Jing Qi et al.
CELL STEM CELL (2015)
Down-regulation of Wt1 activates Wnt/β-catenin signaling through modulating endocytic route of LRP6 in podocyte dysfunction in vitro
Zhou Jing et al.
CELLULAR SIGNALLING (2015)
Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL
Matthew C. Stubbs et al.
CLINICAL CANCER RESEARCH (2015)
The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers
Shirley K. Knauer et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2015)
Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway
Alessandra Leone et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists
Stephane Prost et al.
NATURE (2015)
HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities
Emily Koeneke et al.
CELLS (2015)
Pharmacological targeting of beta-catenin in normal karyotype acute myeloid leukemia blasts
Elizabeth A. Griffiths et al.
HAEMATOLOGICA (2015)
Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells
W. Fiskus et al.
LEUKEMIA (2015)
Role of the Wilms' tumor 1 gene in the aberrant biological behavior of leukemic cells and the related mechanisms
Yan Li et al.
ONCOLOGY REPORTS (2014)
MYC Activation Is a Hallmark of Cancer Initiation and Maintenance
Meital Gabay et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2014)
Tubulin polymerization promoting protein 1 (TPPP1) increases β-catenin expression through inhibition of HDAC6 activity in U2OS osteosarcoma cells
Alice V. Schofield et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
HDAC3 is essential for DNA replication in hematopoietic progenitor cells
Alyssa R. Summers et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/β-Catenin Signaling
Nan Li et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Combined histone deacetylase and cyclooxygenase inhibition achieves enhanced antiangiogenic effects in lung cancer cells
Xiaoqi Wang et al.
MOLECULAR CARCINOGENESIS (2013)
Vorinostat Induces Apoptosis and Differentiation in Myeloid Malignancies: Genetic and Molecular Mechanisms
Gabriela Silva et al.
PLOS ONE (2013)
Inhibition of Histone Deacetylase 3 Causes Replication Stress in Cutaneous T Cell Lymphoma
Christina E. Wells et al.
PLOS ONE (2013)
HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner
Melissa Malvaez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors
Wajana L. Labisso et al.
CELL CYCLE (2012)
Deacetylase inhibitors modulate proliferation and self-renewal properties of leukemic stem and progenitor cells
Annette Romanski et al.
CELL CYCLE (2012)
Genetic and Pharmacologic Inhibition of β-Catenin Targets Imatinib-Resistant Leukemia Stem Cells in CML
Florian H. Heidel et al.
CELL STEM CELL (2012)
Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation
Anthony B. Mak et al.
CELL REPORTS (2012)
Differential niche and Wnt requirements during acute myeloid leukemia progression
Steven W. Lane et al.
BLOOD (2011)
Heterogeneous sensitivity of human acute myeloid leukemia to β-catenin down-modulation
A. Gandillet et al.
LEUKEMIA (2011)
Sulindac Sulfide Reverses Aberrant Self-Renewal of Progenitor Cells Induced by the AML-Associated Fusion Proteins PML/RARα and PLZF/RARα
Gunnar Steinert et al.
PLOS ONE (2011)
β-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells
Jenny Yeung et al.
CANCER CELL (2010)
Inhibition of Histone Deacetylase in Cancer Cells Slows Down Replication Forks, Activates Dormant Origins, and Induces DNA Damage
Chiara Conti et al.
CANCER RESEARCH (2010)
A Novel Wilms Tumor 1 (WT1) Target Gene Negatively Regulates the WNT Signaling Pathway
Myoung Shin Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease
James E. Bradner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
Yingzi Wang et al.
SCIENCE (2010)
Prognostic significance of β-catenin and topoisomerase IIα in de novo acute myeloid leukemia
Chih-Cheng Chen et al.
AMERICAN JOURNAL OF HEMATOLOGY (2009)
53BP1: function and mechanisms of focal recruitment
Jennifer E. FitzGerald et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells
Katharina Salome Minke et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2009)
Dynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiation
Laura M. Green et al.
NUCLEIC ACIDS RESEARCH (2009)
Wt1 negatively regulates β-catenin signaling during testis development
Hao Chang et al.
DEVELOPMENT (2008)
TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels
Mohammad Shahidul Makki et al.
NUCLEIC ACIDS RESEARCH (2008)
Expression of β-catenin by acute myeloid leukemia cells predicts enhanced clonogenic capacities and poor prognosis
L. Ysebaert et al.
LEUKEMIA (2006)
Cytometric assessment of DNA damage in relation to cell cycle phase and apoptosis
X Huang et al.
CELL PROLIFERATION (2005)
Constitutive activation of the Wnt/ß-catenin signalling pathway in acute myeloid leukaemia
M Simon et al.
ONCOGENE (2005)
Transcriptional activation of c-myc proto-oncogene by WT1 protein
YQ Han et al.
ONCOGENE (2004)
Aberrant expression of β-catenin discriminates acute myeloid leukaemia from acute lymphoblastic leukaemia
E Serinsöz et al.
BRITISH JOURNAL OF HAEMATOLOGY (2004)
Effect of nonsteroidal anti-inflammatory drugs on β-catenin protein levels and catenin-related transcription in human colorectal cancer cells
SH Gardner et al.
BRITISH JOURNAL OF CANCER (2004)
Target disruption of the mutant β-catenin gene in colon cancer cell line HCT116:: preservation of its malignant phenotype
S Sekine et al.
ONCOGENE (2002)
Cyclooxygenase-independent actions of cyclooxygenase inhibitors
I Tegeder et al.
FASEB JOURNAL (2001)
Apoptosis-induced cleavage of β-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential
U Steinhusen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
HA Coller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
分享论文
