期刊
JOURNAL FOR IMMUNOTHERAPY OF CANCER
卷 7, 期 1, 页码 -出版社
BMC
DOI: 10.1186/s40425-019-0683-0
关键词
Anti-CTLA-4; Anti-PD-1; Cancer; Combination therapy; Immunotherapy; Immunity; Treatment resistance
资金
- NCATS NIH HHS [UL1 TR001863] Funding Source: Medline
- NCI NIH HHS [P30 CA016042] Funding Source: Medline
As part of the 2018 Immunotherapy Bridge congress (November 28-29, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on four topical clinical issues in immunotherapy today. These were: the relative importance of adaptive versus innate immunity in the anti-cancer immune response; the merits of combination versus sequential immunotherapy regimens in the treatment of cancer; the advantages and disadvantages of murine models of cancer versus humans in order to evaluate immunotherapy; and whether or not mechanisms of resistance to immunotherapy differ between different cancers. Discussion of these important topics are summarised in this report.
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