期刊
FRONTIERS IN CHEMISTRY
卷 7, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fchem.2019.00619
关键词
molecular containers; host-guest complexes; drug delivery; supramolecular chemistry; drug release; molecular recognition; chemosensing
资金
- Alexander von Humboldt Foundation
- SERB, India [EMR/2016/000857]
- DFG [NA-686/8, SPP 1807]
The supramolecular chemistry of cucurbit[n]urils (CBn) has been rapidly developing to encompass diverse medicinal applications, including drug formulation and delivery, controlled drug release, and sensing for bioanalytical purposes. This is made possible by their unique recognition properties and very low cytotoxicity. In this review, we summarize the host-guest complexation of biologically important molecules with CBn, and highlight their implementation in medicinal chemistry and chemical biology.
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