相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Drugs and Scaffold That Inhibit Cytochrome P450 27A1 In Vitro and In Vivo
Morrie Lam et al.
MOLECULAR PHARMACOLOGY (2018)
Structure and function of the cytochrome P450 peroxygenase enzymes
Andrew W. Munro et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2018)
Altered cytokine profile under control of the serotonergic system determines the regulation of CYP2C11 and CYP3A isoforms
Marta Kot et al.
FOOD AND CHEMICAL TOXICOLOGY (2018)
Ontogeny and aging of Nrf2 pathway genes in livers of rats
Shang-Fu Xu et al.
LIFE SCIENCES (2018)
A human relevance investigation of PPARα-mediated key events in the hepatocarcinogenic mode of action of propaquizafop in rats
Christian Strupp et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2018)
Biochemical basis for the age-related sensitivity of broilers to aflatoxin B1
He Wang et al.
TOXICOLOGY MECHANISMS AND METHODS (2018)
Biochemical basis for the age-related sensitivity of broilers to aflatoxin B1
He Wang et al.
TOXICOLOGY MECHANISMS AND METHODS (2018)
Age-associated changes in GSH S-transferase gene/proteins in livers of rats
Shangfu Xu et al.
REDOX REPORT (2018)
In vitro metabolism of specific CYP2D and CYP3A opioid substrates using rat liver S9 fractions and mass spectrometry reveal a severe metabolic impairment with increasing age
Sabrin Fuad Salmin et al.
BIOMEDICAL CHROMATOGRAPHY (2017)
Age-related change of hepatic uridine diphosphate glucuronosyltransferase and sulfotransferase activities in male chickens and pigs
S. X. Hu
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS (2017)
Ontogeny, aging, and gender-related changes in hepatic multidrug resistant protein genes in rats
Qiong-Ni Zhu et al.
LIFE SCIENCES (2017)
Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis
Hui Li et al.
DRUG METABOLISM AND DISPOSITION (2017)
The effect of ageing on isoniazid pharmacokinetics and hepatotoxicity in Fischer 344 rats
John Mach et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2016)
Function and organization of the human cytosolic sulfotransferase (SULT) family
Michael W. H. Coughtrie
CHEMICO-BIOLOGICAL INTERACTIONS (2016)
The immature rat as a potential model for chemical risks to children: Ontogeny of selected hepatic P450s
Brooks T. McPhail et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2016)
Specific features of pharmacokinetics in children
Petra Matalova et al.
DRUG METABOLISM REVIEWS (2016)
Hepatic expression of cytochrome P450 in Zucker diabetic fatty rats
So Young Park et al.
FOOD AND CHEMICAL TOXICOLOGY (2016)
Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children
Elizabeth Neumann et al.
FRONTIERS IN PHARMACOLOGY (2016)
Developmental toxicity of hexachloronaphthalene in Wistar rats. A role of CYP1A1 expression
Anna Kilanowicz et al.
REPRODUCTIVE TOXICOLOGY (2015)
Age-related changes in mRNA levels of hepatic transporters, cytochrome P450 and UDP-glucuronosyltransferase in female rats
Atsushi Kawase et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2015)
Irreversible perinatal imprinting of adult expression of the principal sex-dependent drug-metabolizing enzyme CYP2C11
Rajat Kumar Das et al.
FASEB JOURNAL (2014)
The Aggravation of Clozapine-Induced Hepatotoxicity by Glycyrrhetinic Acid in Rats
Ling-ling Jia et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2014)
The Effect of Aging on Acetaminophen Pharmacokinetics, Toxicity and Nrf2 in Fischer 344 Rats
John Mach et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Potency of Individual Bile Acids to Regulate Bile Acid Synthesis and Transport Genes in Primary Human Hepatocyte Cultures
Jie Liu et al.
TOXICOLOGICAL SCIENCES (2014)
Age- and sex-related differences of organic anion-transporting polypeptide gene expression in livers of rats
Wei-Yu Hou et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)
Developmental expression of drug metabolizing enzymes: Impact on disposition in neonates and young children
R. N. Hines
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
Ulrich M. Zanger et al.
PHARMACOLOGY & THERAPEUTICS (2013)
Ontogeny of mammalian metabolizing enzymes in humans and animals used in toxicological studies
Shakil Ahmed Saghir et al.
CRITICAL REVIEWS IN TOXICOLOGY (2012)
Ontogeny of Hepatic Glucuronidation; Methods and Results
Elke H.J. Krekels et al.
CURRENT DRUG METABOLISM (2012)
Hepatocellular hypertrophy and cell proliferation in Sprague-Dawley rats from dietary exposure to potassium perfluorooctanesulfonate results from increased expression of xenosensor nuclear receptors PPARα and CAR/PXR
Clifford R. Elcombe et al.
TOXICOLOGY (2012)
D2-Dopaminergic Receptor-Linked Pathways: Critical Regulators of CYP3A, CYP2C, and CYP2D
Evangelos P. Daskalopoulos et al.
MOLECULAR PHARMACOLOGY (2012)
Down-Regulation of Hepatic CYP3A and CYP2C Mediated Metabolism in Rats with Moderate Chronic Kidney Disease
Thomas J. Velenosi et al.
DRUG METABOLISM AND DISPOSITION (2012)
Coordinated Regulation of Hepatic Phase I and II Drug-Metabolizing Genes and Transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-Null Mice
Lauren M. Aleksunes et al.
DRUG METABOLISM AND DISPOSITION (2012)
Ontogeny of Novel Cytochrome P450 Gene Isoforms during Postnatal Liver Maturation in Mice
Julia Yue Cui et al.
DRUG METABOLISM AND DISPOSITION (2012)
Age-Related Changes in Pharmacokinetics
Shaojun Shi et al.
CURRENT DRUG METABOLISM (2011)
Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis
Sayeepriyadarshini Anakk et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Kaempferol Regulates the Lipid-Profile in High-Fat Diet-Fed Rats through an Increase in Hepatic PPARα Levels
Chia Ju Chang et al.
PLANTA MEDICA (2011)
Age-related changes in hepatic expression and activity of cytochrome P450 in male rats
Kang Uk Yun et al.
ARCHIVES OF TOXICOLOGY (2010)
Cytochrome P450 mRNA expressions along with in vitro differentiation of hepatocyte precursor cells from fetal, young and old rats
Piotr Czekaj et al.
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA (2010)
Changes in the Gene Expression and Enzyme Activity of Hepatic Cytochrome P450 in Juvenile Sprague-Dawley Rats
Yoshiji Asaoka et al.
JOURNAL OF VETERINARY MEDICAL SCIENCE (2010)
Three Patterns of Cytochrome P450 Gene Expression during Liver Maturation in Mice
Steven N. Hart et al.
DRUG METABOLISM AND DISPOSITION (2009)
Dynamic Patterns of Histone Methylation Are Associated with Ontogenic Expression of the Cyp3a Genes during Mouse Liver Maturation
Ye Li et al.
MOLECULAR PHARMACOLOGY (2009)
The ontogeny of drug metabolism enzymes and implications for adverse drug events
Ronald N. Hines
PHARMACOLOGY & THERAPEUTICS (2008)
The ontogeny of drug metabolizing enzymes and transporters in the rat
Loeckie de Zwart et al.
REPRODUCTIVE TOXICOLOGY (2008)
Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity
Jin Seok Kang et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2008)
Expression of hepatic UDP-glucuronosyltransferase 1A1 and 1A6 correlated with increased expression of the nuclear constitutive androstane receptor and peroxisome proliferator-activated receptor α in male rats fed a high-fat and high-sucrose diet
Makoto Osabe et al.
DRUG METABOLISM AND DISPOSITION (2008)
Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis
Susana Cuesta de Juan et al.
JOURNAL OF LIPID RESEARCH (2007)
Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat
Fawzy A. Elbarbry et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2007)
Hepatic transcript levels for genes coding for enzymes associated with xenobiotic metabolism are altered with age
Kazuhiko Mori et al.
TOXICOLOGIC PATHOLOGY (2007)
The effect of ageing on cytochrome P450 enzymes: Consequences for drug biotransformation in the elderly
V. Wauthier et al.
CURRENT MEDICINAL CHEMISTRY (2007)
Effects of pregnancy on CYPs protein expression in rat liver
XJ He et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2005)
Age-related differences in CYP3A expression and activity in the rat liver, intestine, and kidney
JS Warrington et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Constitutive and inducible hepatic cytochrome P450 isoforms in senescent male and female rats and response to low-dose phenobarbital
AK Agrawal et al.
DRUG METABOLISM AND DISPOSITION (2003)
Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism - Focus on in vitro studies
MT Donato et al.
CLINICAL PHARMACOKINETICS (2003)