相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Autophagy in cardiomyopathies
Antonia T. L. Zech et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2020)
Lysosome biogenesis in health and disease
Lakshya Bajaj et al.
JOURNAL OF NEUROCHEMISTRY (2019)
The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species
Didac Carmona-Gutierrez et al.
NATURE COMMUNICATIONS (2019)
Filamentous Aggregates Are Fragmented by the Proteasome Holoenzyme
Rachel Cliffe et al.
CELL REPORTS (2019)
Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization
Xiucui Ma et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2019)
PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against cardiac proteinopathy
Hanming Zhang et al.
SCIENCE ADVANCES (2019)
Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs
Paul A. Parcon et al.
ALZHEIMERS & DEMENTIA (2018)
The Role of Autophagy in the Heart
Sebastiano Sciarretta et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 80 (2018)
Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure
Peter P. Rainer et al.
CIRCULATION RESEARCH (2018)
Cardiac proteasome functional insufficiency plays a pathogenic role in diabetic cardiomyopathy
Jie Li et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2017)
TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux
Bo Pan et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2017)
Inhibition of Mutant αB Crystallin-Induced Protein Aggregation by a Molecular Tweezer
Na Xu et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2017)
Multistep regulation of TFEB by MTORC1
Silvia Vega-Rubin-de-Celis et al.
AUTOPHAGY (2017)
Activation of Autophagy Ameliorates Cardiomyopathy in Mybpc3-Targeted Knockin Mice
Sonia R. Singh et al.
CIRCULATION-HEART FAILURE (2017)
Autophagy modulation: a potential therapeutic approach in cardiac hypertrophy
Xuejun Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2017)
Myocardial Upregulation of Cathepsin D by Ischemic Heart Disease Promotes Autophagic Flux and Protects Against Cardiac Remodeling and Heart Failure
Penglong Wu et al.
CIRCULATION-HEART FAILURE (2017)
Aβ Amyloid Pathology Affects the Hearts of Patients With Alzheimer's Disease
Luca Troncone et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)
Disruption of desmin-mitochondrial architecture in patients with regurgitant mitral valves and preserved ventricular function
Mustafa I. Ahmed et al.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2016)
Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors
Lei Zhang et al.
MOLECULAR ONCOLOGY (2016)
Cardioprotection and lifespan extension by the natural polyamine spermidine
Tobias Eisenberg et al.
NATURE MEDICINE (2016)
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
Heidi Martini-Stoica et al.
TRENDS IN NEUROSCIENCES (2016)
Untangling Autophagy Measurements All Fluxed Up
Roberta A. Gottlieb et al.
CIRCULATION RESEARCH (2015)
mTOR: a pharmacologic target for autophagy regulation
Young Chul Kim et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Cofilin-2 Phosphorylation and Sequestration in Myocardial Aggregates Novel Pathogenetic Mechanisms for Idiopathic Dilated Cardiomyopathy
Khaushik Subramanian et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2015)
Reviving the protein quality control system: Therapeutic target for cardiac disease in the elderly
Roelien A. M. Meijering et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2015)
A molecular tweezer antagonizes seminal amyloids and HIV infection
Edina Lump et al.
ELIFE (2015)
Proteasomal and lysosomal protein degradation and heart disease
Xuejun Wang et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Proteotoxicity: An underappreciated pathology in cardiac disease
Marco Sandri et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
c-Abl Tyrosine Kinase Mediates Neurotoxic Prion Peptide-Induced Neuronal Apoptosis via Regulating Mitochondrial Homeostasis
Bo Pan et al.
MOLECULAR NEUROBIOLOGY (2014)
Altered ubiquitin-proteasome signaling in right ventricular hypertrophy and failure
Viswanathan Rajagopalan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
Protein Kinase G Positively Regulates Proteasome-Mediated Degradation of Misfolded Proteins
Mark J. Ranek et al.
CIRCULATION (2013)
Posttranslational Modification and Quality Control
Xuejun Wang et al.
CIRCULATION RESEARCH (2013)
Impaired Assembly and Post-translational Regulation of 26S Proteasome in Human End-Stage Heart Failure
Sharlene M. Day et al.
CIRCULATION-HEART FAILURE (2013)
Enhanced autophagy ameliorates cardiac proteinopathy
Md. Shenuarin Bhuiyan et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Mechanisms of Disease Proteotoxicity and Cardiac Dysfunction - Alzheimer's Disease of the Heart?
Monte S. Willis et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
Mickael Decressac et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
Jose A. Martina et al.
AUTOPHAGY (2012)
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
Carmine Settembre et al.
EMBO JOURNAL (2012)
A Novel Molecular Tweezer Inhibitor of α-Synuclein Neurotoxicity in Vitro and in Vivo
Shubhangi Prabhudesai et al.
NEUROTHERAPEUTICS (2012)
The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
Agnes Roczniak-Ferguson et al.
SCIENCE SIGNALING (2012)
PGC-1α Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function
Taiji Tsunemi et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Desmin-related cardiomyopathy: an unfolding story
Patrick M. McLendon et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
Proteasome functional insufficiency in cardiac pathogenesis
Xuejun Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
Autophagy and p62 in Cardiac Proteinopathy
Qingwen Zheng et al.
CIRCULATION RESEARCH (2011)
Atg7 Induces Basal Autophagy and Rescues Autophagic Deficiency in CryABR120G Cardiomyocytes
J. Scott Pattison et al.
CIRCULATION RESEARCH (2011)
Enhancement of proteasome function by PA28α overexpression protects against oxidative stress
Jie Li et al.
FASEB JOURNAL (2011)
Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
Michela Palmieri et al.
HUMAN MOLECULAR GENETICS (2011)
Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice
Jie Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
TFEB Links Autophagy to Lysosomal Biogenesis
Carmine Settembre et al.
SCIENCE (2011)
Ubiquitin Proteasome Dysfunction in Human Hypertrophic and Dilated Cardiomyopathies
Jaime M. Predmore et al.
CIRCULATION (2010)
Protein Aggregates and Novel Presenilin Gene Variants in Idiopathic Dilated Cardiomyopathy
Davide Gianni et al.
CIRCULATION (2010)
Pathogenic Lysosomal Depletion in Parkinson's Disease
Benjamin Dehay et al.
JOURNAL OF NEUROSCIENCE (2010)
Tragedy in a heartbeat: malfunctioning desmin causes skeletal and cardiac muscle disease
Lev G. Goldfarb et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Protective Effect of Geranylgeranylacetone via Enhancement of HSPB8 Induction in Desmin-Related Cardiomyopathy
Atsushi Sanbe et al.
PLOS ONE (2009)
A Gene Network Regulating Lysosomal Biogenesis and Function
Marco Sardiello et al.
SCIENCE (2009)
Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy
Paul Tannous et al.
CIRCULATION (2008)
Autophagy is an adaptive response in desmin-related cardiomyopathy
Paul Tannous et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Human αB-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice
Namakkal S. Rajasekaran et al.
CELL (2007)
Interruption of CryAB-Amyloid oligomer formation by HSP22
Atsushi Sanbe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Heart failure and protein quality control
Xuejun Wang et al.
CIRCULATION RESEARCH (2006)
Aberrant protein aggregation is essential for a mutant desmin to impair the proteolytic function of the ubiquitin-proteasome system in cardiomyocytes
JB Liu et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2006)
Intrasarcoplasmic amyloidosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake
QH Chen et al.
CIRCULATION RESEARCH (2005)
Desmin-related cardiomyopathy in transgenic mice: A cardiac amyloidosis
A Sanbe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Upregulation of the transcription factor TFEB in t(6;11)(p21;q13)-positive renal cell carcinomas due to promoter substitution
RP Kuiper et al.
HUMAN MOLECULAR GENETICS (2003)
Hyperubiquitination of proteins in dilated cardiomyopathy
J Weekes et al.
PROTEOMICS (2003)
Expression of R120G-αB-crystallin causes aberrant desmin and αB-crystallin aggregation and cardiomyopathy in mice
XJ Wang et al.
CIRCULATION RESEARCH (2001)
Impairment of the ubiquitin-proteasome system by protein aggregation
NF Bence et al.
SCIENCE (2001)
Mouse model of desmin-related cardiomyopathy
XJ Wang et al.
CIRCULATION (2001)
分享论文
