期刊
FRONTIERS IN NEUROSCIENCE
卷 13, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fnins.2019.00936
关键词
deep brain stimulation; neuromodulation; epilepsy; Parkinson's disease; tremor; optogenetics; Tourette syndrome; temporal dispersion
资金
- National Parkinson Foundation
- NIH, foundation
- European Union [720270, UL1TR001409]
- National Center for Advancing Translational Sciences (NCATS)
- National Institutes of Health, through the Clinical and Translational Science Awards Program (CTSA)
- Department of Health and Human Services, part of the Roadmap Initiative
- AEHS Foundation
- Austin and Ann O'Malley Visiting Chair in Bioethics of Loyola Marymount University
- HHMI-Simons Faculty Scholars Program
- Open Philanthropy Project, Human Frontier Science Program [RGP0015/2016]
- US Army Research Laboratory
- US Army Research Office [W911NF1510548]
- US-Israel Binational Science Foundation [2014509]
- NIH
- National Institutes of Health (NIH) [R01-EB006136, R01-NS095291]
- PECASE, National Institute on Aging [R01AG047664, U01NS090577]
- SPARC grant [OT2OD023848-01]
- Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office
- NSF NeuroNex Technology Hub grant [1707316]
- Curci Foundation
- Beckman Institute
- Rosen Center at Caltech
- NIH/NCATS Clinical and Translational Science Awards [UL1TR001427, KL2TR001429, TL1TR001428]
- National Institutes of Health
- Defense Advanced Research Projects Agency (DARPA)
- DARPA Restoring Active Memory (RAM) program [N66001-14-2-4032]
- Boston Scientific Neuromodulation
- Neuros Medical
- NIH National Institute of Neurological Disorders and Stroke [K23NS083741]
- Dystonia Medical Research Foundation
- NINDS Grant [5 R21 NS096398-02]
- Michael J. Fox Foundation
- Robert and Ruth Halperin Foundation
- John A. Blume Foundation
- Helen M. Cahill Award for Research in Parkinson's Disease
- NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative [UH3NS103550]
- Hope for Depression Research Foundation [UH3NS103549, R01NS097782, U01NS098961]
- National Institute of Neurological Disorders and Stroke (NINDS)
- Brain and Behavior Research Foundation (National Alliance for Research on Schizophrenia and Depression Young Investigator Grant)
- Parkinson's Disease Foundation
- NIH Intramural Research Program - Whitehall Research grant [2017-12-54]
- University of Minnesota Udall center [P50NS098573]
- NIH NINDS [NS092730]
- National Science Foundation [EEC-1028725]
- Department of Defense through the National Defense and Engineering Graduate Fellowship program
- UC President's Postdoctoral Fellowship
- Parkinson Alliance
- Smallwood Foundation
- BachmannStrauss Foundation
- Tourette Syndrome Association
- UF Foundation [R01 NR014852, R01NS096008]
- PeerView
- QuantiaMD
- MedNet
- Vanderbilt University
- Abbvie
- Allergan
The annual deep brain stimulation (DBS) Think Tank aims to create an opportunity for a multidisciplinary discussion in the field of neuromodulation to examine developments, opportunities and challenges in the field. The proceedings of the Sixth Annual Think Tank recapitulate progress in applications of neurotechnology, neurophysiology, and emerging techniques for the treatment of a range of psychiatric and neurological conditions including Parkinson's disease, essential tremor, Tourette syndrome, epilepsy, cognitive disorders, and addiction. Each section of this overview provides insight about the understanding of neuromodulation for specific disease and discusses current challenges and future directions. This year's report addresses key issues in implementing advanced neurophysiological techniques, evolving use of novel modulation techniques to deliver DBS, ans improved neuroimaging techniques. The proceedings also offer insights into the new era of brain network neuromodulation and connectomic DBS to define and target dysfunctional brain networks. The proceedings also focused on innovations in applications and understanding of adaptive DBS (closed-loop systems), the use and applications of optogenetics in the field of neurostimulation and the need to develop databases for DBS indications. Finally, updates on neuroethical, legal, social, and policy issues relevant to DBS research are discussed.
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