期刊
ACS CATALYSIS
卷 9, 期 10, 页码 9110-9116出版社
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.9b02623
关键词
homogeneous catalysis; hydrosilylation; cyclopropanes; asymmetric catalysis; rhodium
资金
- National Natural Science Foundation of China [NSFC 21702211, 21703051, 21773051]
- Zhejiang Provincial Natural Science Foundation of China [LZ18B020001, LY17B030005, LY18B020013]
Catalytic hydrosilylation of alkenes ranks as one of the most important academic and industrial synthetic reactions in homogeneous catalysis and organosilicon chemistry. In this work, a highly enantioselective Rh-catalyzed desymmetric hydrosilylation reaction of 1,1-disubstituted cyclopropenes with the promotion of chiral DTBM-SEGPHOS is described. It allows for a straightforward access to potentially valuable chiral organosilicon compounds bearing a carbon quaternary stereocenter in high yields with good diastereo- and enantioselectivities (up to >99:1 d.r. and >99% ee) in a 100% atom-efficient manner from readily available starting cyclopropenes and hydrosilanes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据