4.5 Article

HOX genes as transcriptional and epigenetic regulators during tumorigenesis and their value as therapeutic targets

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Peptide therapeutics that directly target transcription factors

Ichiro Inamoto et al.

PEPTIDE SCIENCE (2019)

Review Cell Biology

HOTAIR: An Oncogenic Long Non-Coding RNA in Human Cancer

Qing Tang et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)

Review Biochemistry & Molecular Biology

Defining Driver DNA Methylation Changes in Human Cancer

Gerd P. Pfeifer

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Cell & Tissue Engineering

Role of HOX Genes in Stem Cell Differentiation and Cancer

Seema Bhatlekar et al.

STEM CELLS INTERNATIONAL (2018)

Article Multidisciplinary Sciences

A meta-analysis on the role of pleiotrophin (PTN) as a prognostic factor in cancer

Jiupeng Zhou et al.

PLOS ONE (2018)

Article Biotechnology & Applied Microbiology

Homeobox oncogene activation by pan-cancer DNA hypermethylation

Jianzhong Su et al.

GENOME BIOLOGY (2018)

Article Developmental Biology

A systematic survey of HOX and TALE expression profiling in human cancers

Yunlong Jia et al.

INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2018)

Article

Targeting HOX/PBX dimers in cancer

Richard Morgan et al.

Oncotarget (2017)

Review Dentistry, Oral Surgery & Medicine

The role of HOX genes in head and neck squamous cell carcinoma

Christopher Platais et al.

JOURNAL OF ORAL PATHOLOGY & MEDICINE (2016)

Review Oncology

The Widening Sphere of Influence of HOXB7 in Solid Tumors

Maria Cristina Errico et al.

CANCER RESEARCH (2016)

Review Biotechnology & Applied Microbiology

Methylation status of homeobox genes in common human cancers

Maria Fernanda Setubal Destro Rodrigues et al.

GENOMICS (2016)

Article Multidisciplinary Sciences

A Conserved Structural Signature of the Homeobox Coding DNA in HOX genes

Bernard Fongang et al.

SCIENTIFIC REPORTS (2016)

Article Multidisciplinary Sciences

Identification and validation of candidate epigenetic biomarkers in lung adenocarcinoma

Iben Daugaard et al.

SCIENTIFIC REPORTS (2016)

Article Biochemistry & Molecular Biology

The role of HOXB2 and HOXB3 in acute myeloid leukemia

Oscar Lindblad et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Article Multidisciplinary Sciences

Induction of p53-independent apoptosis by ectopic expression of HOXA5 in human liposarcomas

Dhong Hyun Lee et al.

SCIENTIFIC REPORTS (2015)

Review Zoology

Did homeobox gene duplications contribute to the Cambrian explosion?

Peter W. H. Holland

ZOOLOGICAL LETTERS (2015)

Review Genetics & Heredity

HOX genes and their role in the development of human cancers

Seema Bhatlekar et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2014)

Review Endocrinology & Metabolism

Human HOX gene disorders

Shane C. Quinonez et al.

MOLECULAR GENETICS AND METABOLISM (2014)

Article Urology & Nephrology

Targeting HOX transcription factors in prostate cancer

Richard Morgan et al.

BMC UROLOGY (2014)

Review Medical Laboratory Technology

Gene methylation in gastric cancer

Yiping Qu et al.

CLINICA CHIMICA ACTA (2013)

Review Developmental Biology

The regulation of Hox gene expression during animal development

Moises Mallo et al.

DEVELOPMENT (2013)

Review Pharmacology & Pharmacy

Future directions for peptide therapeutics development

Allan A. Kaspar et al.

DRUG DISCOVERY TODAY (2013)

Article Obstetrics & Gynecology

EMX2 is Downregulated in Endometrial Cancer and Correlated With Tumor Progression

Haifeng Qiu et al.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY (2013)

Review Biotechnology & Applied Microbiology

Gene Silencing and Polycomb Group Proteins: An Overview of their Structure, Mechanisms and Phylogenetics

Shahram Golbabapour et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2013)

Review Biology

Hox Targets and Cellular Functions

Ernesto Sanchez-Herrero

SCIENTIFICA (2013)

Article Multidisciplinary Sciences

The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway

Kideok Jin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Reproductive Biology

HOX genes in ovarian cancer

Zoe L. Kelly et al.

JOURNAL OF OVARIAN RESEARCH (2011)

Article Pathology

Influence of Hoxa5 on p53 Tumorigenic Outcome in Mice

Gaelle Gendronneau et al.

AMERICAN JOURNAL OF PATHOLOGY (2010)

Article Oncology

Targeting HOX and PBX transcription factors in ovarian cancer

Richard Morgan et al.

BMC CANCER (2010)

Article Biotechnology & Applied Microbiology

Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated

Mun-Kit Choy et al.

BMC GENOMICS (2010)

Article Medicine, Research & Experimental

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype

Penney M. Gilbert et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Multidisciplinary Sciences

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

Rajnish A. Gupta et al.

NATURE (2010)

Review Oncology

The Hox genes and their roles in oncogenesis

Nilay Shah et al.

NATURE REVIEWS CANCER (2010)

Article Biochemistry & Molecular Biology

Epigenetic Silencing of the RASSF1A Tumor Suppressor Gene through HOXB3-Mediated Induction of DNMT3B Expression

Rajendra Kumar Palakurthy et al.

MOLECULAR CELL (2009)

Review Oncology

p21 in cancer: intricate networks and multiple activities

Tarek Abbas et al.

NATURE REVIEWS CANCER (2009)

Article Multidisciplinary Sciences

HOXB13 promotes ovarian cancer progression

Jiangyong Miao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Oncology

A role for the HOXB7 homeodomain protein in DNA repair

Ethel Rubin et al.

CANCER RESEARCH (2007)

Article Biochemistry & Molecular Biology

Miracles in hox gene regulation

VS Chopra et al.

BIOESSAYS (2006)

Article Oncology

HOXA5 regulates hMLH1 expression in breast cancer cells

Sai Duriseti et al.

NEOPLASIA (2006)

Review Developmental Biology

Hox cofactors in vertebrate development

CB Moens et al.

DEVELOPMENTAL BIOLOGY (2006)

Review Genetics & Heredity

The genesis and evolution of homeobox gene clusters

J Garcia-Fernàndez

NATURE REVIEWS GENETICS (2005)

Article Biochemistry & Molecular Biology

Two rounds of whole genome duplication in the ancestral vertebrate

P Dehal et al.

PLOS BIOLOGY (2005)

Article Cell Biology

Hox genes specify vertebral types in the presomitic mesoderm

M Carapuço et al.

GENES & DEVELOPMENT (2005)

Article Biochemistry & Molecular Biology

Identification of transcriptional targets of HOXA5

HX Chen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8

HX Chen et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Biology

The duplication of the Hox gene clusters in teleost fishes

SJ Prohaska et al.

THEORY IN BIOSCIENCES (2004)

Article Biochemistry & Molecular Biology

The direct context of a hox retinoic acid response element is crucial for its activity

T Oosterveen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Human growth hormone-regulated HOXA1 is a human mammary epithelial oncogene

X Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Transcriptional repression of peri-implantation EMX2 expression in mammalian reproduction by HOXA10

PJ Troy et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Multidisciplinary Sciences

The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

F Chédin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Cell Biology

p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells

VC Bromleigh et al.

GENES & DEVELOPMENT (2000)

Article Multidisciplinary Sciences

Compromised HOXA5 function can limit p53 expression in human breast tumours

V Raman et al.

NATURE (2000)