期刊
TETRAHEDRON LETTERS
卷 60, 期 34, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2019.150987
关键词
CO2 plasticizing polymerization; Organocatalysis; Polylactide; Supercritical fluid
资金
- Ministry of Education, Culture, Sports, Science and Technology (MEXT) [JP24105511, JP 26105722]
Herein, an efficient (>95% yield, >99.0% ee) Bronsted acid-catalyzed synthetic method of poly-L-lactide (PLLA) in supercritical carbon dioxide (scCO(2)) under plasticizing conditions is presented. High-performance liquid chromatography analysis of the PLLA hydrolysis products indicated that, as opposed to the case of organic solvents, the use of a nucleophilic catalyst in scCO(2) suppressed the epimerization. The highly stereochemically pure PLLA prepared by the developed method under metal-free conditions meets the criteria of medicinal/engineering applications. (C) 2019 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据