期刊
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
卷 219, 期 -, 页码 257-266出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.saa.2019.04.055
关键词
Raman spectroscopy; Lung tissues; Cancer diagnosis; PCA-WA
类别
资金
- Operational Programme Prague Competitiveness [2.16/3.1.00/24503 and/21537]
- National Program of Sustainability I (NPU MSMT) [LO1601-43760/2015]
- Specific University Research MSMT [21-SVV/2019]
Raman spectroscopy is non-destructive method that allows monitoring of biological tissues with minimal intervention. FT-Raman (lambda(ex) 1064 nm) and NIR-Vis-Raman (lambda(ex) 785 nm) spectroscopic measurements were used in ex vivo analysis of normal. non-cancerous abnormal and cancerous lung tissues. Spectroscopic discrimination of the lung tissue samples was made by the use of the ratio of characteristic bands and multivariate statistical methods (PCA, IDA). The combination of Raman spectroscopy and multivariate statistics may have a diagnostic potential for recognizing of cancer lesions in lung. (C) 2019 Published by Elsevier B.V.
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