4.6 Review

Extracellular vesicles in cancer nanomedicine

期刊

SEMINARS IN CANCER BIOLOGY
卷 69, 期 -, 页码 212-225

出版社

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcancer.2019.08.017

关键词

Cancer; Exosomes; Nanodrug delivery; Vaccines; Extracellular vesicles

类别

资金

  1. Russian Academic Excellence project 5100
  2. Ministry of Science and High Education of the Russian Federation
  3. project of RAS Program Fundamental Research for Biomedical Technologies' (IPAC, RAS Chernogolovka, Moscow Region, Russia)
  4. [14.613.21.0086]
  5. [RFMEFI61318X0086]

向作者/读者索取更多资源

This review explores the application of extracellular vesicles (EVs) as natural nanoparticles for drug delivery in cancer therapy, discussing aspects such as biogenesis, isolation, targeting, and loading of EVs. This research sheds light on the potential of EVs for targeted chemotherapy, gene therapy, and vaccine development.
To date, a lot of nanotechnological optitions are available for targeted drug delivery. Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy, gene therapy, and vaccine development. Aspects of biogenesis, isolation, targeting, and loading of EVs are discussed in detail.

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