期刊
SEMINARS IN CANCER BIOLOGY
卷 69, 期 -, 页码 190-199出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcancer.2019.08.028
关键词
Nano-drugs; Nano-technology; Cancer; Drug delivery; Oncotarget
类别
资金
- Ministry of Science and High Education of the Russian Federation [14.613.21.0086, RFMEFI61318 x 0086]
- Russian Academic Excellence project 5-100''
The use of nanoparticles in anticancer drugs improves safety and efficacy, with advantages such as effective targeting, delayed release, increased half-life, and reduced systemic toxicity. Nano-carriers have shown significant improvements in drug delivery compared to traditional administration, but there are still limitations in their clinical use.
The use of nanoparticles dramatically increases the safety and efficacy of the most common anticancer drugs. The main advantages of nano-drugs and delivery systems based on nano-technology are effective targeting, delayed release, increased half-life, and less systemic toxicity. The use of nano-carriers has led to significant improvements in drug delivery to targets compared with traditional administration of these drugs. In this review, the main tendencies in nano-drug formulations as well as factors limiting their use in clinical settings are discussed. Additionally, the current status of approved nano-drugs for cancer treatment is reviewed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据