期刊
SCIENCE
卷 365, 期 6460, 页码 1405-1408出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aay0240
关键词
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资金
- National Institutes of Health [F32-GM119238]
- Packard Fellowship in Science and Engineering
- Chan Zuckerberg Initiative Ben Barres Career Acceleration Award
Microbial communities associated with animals exert powerful influences on host physiology, regulating metabolism and immune function, as well as complex host behaviors. The importance of host-microbiome interactions for maintaining homeostasis and promoting health raises evolutionarily complicated questions about how animals and their microbiomes have coevolved and how these relationships affect the ways that animals interact with their environment. Here, we review the literature on the contributions of host factors to microbial community structure and corresponding influences of microbiomes on emergent host phenotypes. We focus in particular on animal behaviors as a basis for understanding potential roles for the microbiome in shaping host neurobiology.
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