Pregnant women with confirmed neoplasms should not have noninvasive prenatal testing

What's already known about this topic? Incidental diagnoses of an occult maternal malignancy have been reported upon aberrant routine noninvasive prenatal testing (NIPT). The presence of tumor-derived cell-free DNA in the maternal circulation can skew the NIPT profile. What does this study add? Pregnant women with a confirmed neoplastic disease should not have NIPT testing for fetal aneuploidy screening since NIPT results cannot accurately be applied to assess the fetal chromosomal constitution in this condition.