相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Protein phosphatase 2A A regulates A protein expression and stability
Caitlin M. O'Connor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis
Sarah E. Taylor et al.
CANCER RESEARCH (2019)
Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer
Kimberly McClinch et al.
CANCER RESEARCH (2018)
PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells
Otto Kauko et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
Jaya Sangodkar et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
ProHits-viz: a suite of web tools for visualizing interaction proteomics data
James D. R. Knight et al.
NATURE METHODS (2017)
The KSEA App: a web-based tool for kinase activity inference from quantitative phosphoproteomics
Danica D. Wiredja et al.
BIOINFORMATICS (2017)
A Targeted Mass Spectrometry Assay for Detection of HIV Gag Protein Following Induction of Latent Viral Reservoirs
Daniela Schlatzer et al.
ANALYTICAL CHEMISTRY (2017)
All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase
Jaya Sangodkar et al.
FEBS JOURNAL (2016)
The Reactome pathway Knowledgebase
Antonio Fabregat et al.
NUCLEIC ACIDS RESEARCH (2016)
Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth
Dorien Haesen et al.
CANCER RESEARCH (2016)
HTMD: High-Throughput Molecular Dynamics for Molecular Discovery
S. Doerr et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2016)
The ORFeome Collaboration: a genome-scale human ORF-clone resource
Stefan Wiemann et al.
NATURE METHODS (2016)
Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway
Ae Lee Jeong et al.
SCIENTIFIC REPORTS (2016)
Targeted mutation analysis of endometrial clear cell carcinoma
Lien N. Hoang et al.
HISTOPATHOLOGY (2015)
Comprehensive assessment of cancer missense mutation clustering in protein structures
Atanas Kamburov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling
Otto Kauko et al.
SCIENTIFIC REPORTS (2015)
MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road
Christopher J. Caunt et al.
NATURE REVIEWS CANCER (2015)
Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions
John H. Morris et al.
NATURE PROTOCOLS (2014)
Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
Parthasarathy Seshacharyulu et al.
CANCER LETTERS (2013)
The CRAPome: a contaminant repository for affinity purification-mass spectrometry data
Dattatreya Mellacheruvu et al.
NATURE METHODS (2013)
Kinase-Substrate Enrichment Analysis Provides Insights into the Heterogeneity of Signaling Pathway Activation in Leukemia Cells
Pedro Casado et al.
SCIENCE SIGNALING (2013)
Complex Energy Landscape of a Giant Repeat Protein
Maksym Tsytlonok et al.
STRUCTURE (2013)
Tumor Microenvironmental Signaling Elicits Epithelial-Mesenchymal Plasticity through Cooperation with Transforming Genetic Events
Damian J. Junk et al.
NEOPLASIA (2013)
Enhanced Apoptosis and Tumor Growth Suppression Elicited by Combination of MEK (Selumetinib) and mTOR Kinase Inhibitors (AZD8055)
Sarah V. Holt et al.
CANCER RESEARCH (2012)
Mouse model for probing tumor suppressor activity of protein phosphatase 2A in diverse signaling pathways
Gernot Walter et al.
CELL CYCLE (2012)
Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models
Patrick J. Roberts et al.
CLINICAL CANCER RESEARCH (2012)
The importance of slow motions for protein functional loops
Aris Skliros et al.
PHYSICAL BIOLOGY (2012)
Somatic Mutations of PPP2R1A in Ovarian and Uterine Carcinomas
Ie-Ming Shih et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Human Cancer-Associated Mutations in the Aα Subunit of Protein Phosphatase 2A Increase Lung Cancer Incidence in Aα Knock-In and Knockout Mice
Ralf Ruediger et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Mapping of signaling networks through synthetic genetic interaction analysis by RNAi
Thomas Horn et al.
NATURE METHODS (2011)
TGF-β signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells
Rocky Cipriano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Identification of PP2A Complexes and Pathways Involved in Cell Transformation
Anna A. Sablina et al.
CANCER RESEARCH (2010)
PR65, the HEAT-repeat scaffold of phosphatase PP2A, is an elastic connector that links force and catalysis
Alison Grinthal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
Sian Jones et al.
SCIENCE (2010)
Molecular Distinctions between Stasis and Telomere Attrition Senescence Barriers Shown by Long-term Culture of Normal Human Mammary Epithelial Cells
James C. Garbe et al.
CANCER RESEARCH (2009)
Serine/Threonine Phosphatases: Mechanism through Structure
Yigong Shi
CELL (2009)
ACEMD: Accelerating Biomolecular Dynamics in the Microsecond Time Scale
M. J. Harvey et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2009)
Reconstructing the Equilibrium Boltzmann Distribution from Well-Tempered Metadynamics
M. Bonomi et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Universal sample preparation method for proteome analysis
Jacek R. Wisniewski et al.
NATURE METHODS (2009)
GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation
Berk Hess et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2008)
The tumor suppressor PP2A Aβ regulates the RaIA GTPase
Anna A. Sablina et al.
CELL (2007)
The Amber biomolecular simulation programs
DA Case et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
Cancer-associated PP2A Aα subunits induce functional haploinsufficiency and tumorigenicity
W Chen et al.
CANCER RESEARCH (2005)
Identification of specific PP2A complexes involved in human cell transformation
W Chen et al.
CANCER CELL (2004)
Species- and cell type-specific requirements for cellular transformation
A Rangarajan et al.
CANCER CELL (2004)
A modified TIP3P water potential for simulation with Ewald summation
DJ Price et al.
JOURNAL OF CHEMICAL PHYSICS (2004)
Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival
S Strack et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Characterization of the Aα and Aβ subunit isoforms of protein phosphatase 2A:: differences in expression, subunit interaction, and evolution
J Zhou et al.
BIOCHEMICAL JOURNAL (2003)
Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the Aβ subunit gene
R Ruediger et al.
ONCOGENE (2001)
Low frequency of alterations of the α (PPP2R1A) and β (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms
GA Calin et al.
ONCOGENE (2000)