4.6 Article

Facile Synthesis of a Series of Non-Symmetric Thioethers Including a Benzothiazole Moiety and Their Use as Efficient In Vitro anti-Trypanosoma cruzi Agents

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MOLECULES
卷 24, 期 17, 页码 -

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MDPI
DOI: 10.3390/molecules24173077

关键词

Trypanosoma cruzi; Chagas disease; benzothiazole derivatives; non-symmetric thioethers; neglected diseases

资金

  1. CONACYT [62267]
  2. SIP-IPN [20170697, 2018500]
  3. PAPIIT [IN207317]

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A series of 2-benzylsulfanyl benzothiazole (BTA) derivatives were synthesized and fully characterized and in vitro tested against two strains of T. cruzi (NINOA and INC-5), exhibiting good activities at low concentrations.

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