期刊
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
卷 52, 期 2, 页码 490-497出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/MSS.0000000000002140
关键词
ADIPOSE TISSUE; ABDOMINAL OBESITY; INDIVIDUAL VARIABILITY; AEROBIC EXERCISE
资金
- Canadian Institutes of Health Research [OHN-63277]
Purpose (1) Determine the effect of exercise amount and intensity on the proportion of individuals for whom the adipose tissue (AT) response is above the minimal clinically important difference (MCID); and (2) Examine whether clinically meaningful anthropometric changes reflect individual AT responses above the MCID. Methods Men (n = 41) and women (n = 62) (52.7 7.6 yr) were randomized to control (n = 20); low amount low intensity (n = 24); high amount low intensity (n = 30); and high amount high intensity (n = 29) treadmill exercise for 24 wk. The AT changes were measured by MRI. 90% confidence intervals for each individual's observed response were calculated as the observed score 1.64 x TE (technical error of measurement). Results For visceral AT, HAHI and HALI had a greater proportion of individuals whose AT change and 90% confidence interval were beyond the MCID compared to controls (P < 0.006). For all other AT depots, all exercise groups had significantly more individuals whose changes were beyond the MCID compared with controls. Of those who achieved a waist circumference or body weight reduction the MCID, 76% to 93% achieved abdominal, abdominal subcutaneous, and visceral AT changes >= the MCID. Conclusions Increasing exercise amount and/or intensity may increase the proportion of individuals who achieve clinically meaningful visceral AT reductions. Waist circumference or body weight changes beyond a clinically meaningful threshold are predictive of clinically meaningful abdominal adiposity changes.
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