Application of molecular imprinting polymer anchored on CdTe quantum dots for the detection of sulfadiazine in seawater

A molecularly imprinted polymer (MIP) anchored on the surface of CdTe quantum dots (QDs) was fabricated and used as a fluorescent probe for sulfadiazine (SDZ) detection in seawater. CdTe QDs was used as photoluminescent material, SDZ as the template, 3-aminopropyltriethoxysilane (APTES) as the functional monomer and tetraethyl orthosilicate (TEOS) as the cross-linking agent. Characterizations of MIP-QDs were analyzed by Fourier transform infrared (FT-IR), Transmission electron microscopy (TEM) and Scanning electron microscope (SEM). The conditions were optimized for the detection of MIP-QDs to SDZ. The mechanism of fluorescence quenching was studied by UV-Vis absorption spectroscopy and fluorescence spectroscopy. Under optimal conditions, the fluorescence intensity of MIP-QDs decreased linearly between 4- and 20 mu M SDZ with a good correlation coefficient of 0.995. The limit of detection is 0.67 mu M and the recovery is between 91.8 and 109.4% with RSD lower than 3.9%. These results indicated that MIP-QDs for SDZ detection in seawater was developed successfully.