Field drift correction of proton resonance frequency shift temperature mapping with multichannel fast alternating nonselective free induction decay readouts

Purpose To demonstrate that proton resonance frequency shift MR thermometry (PRFS-MRT) acquisition with nonselective free induction decay (FID), combined with coil sensitivity profiles, allows spatially resolved B-0 drift-corrected thermometry. Methods Phantom experiments were performed at 1.5T and 3T. Acquisition of PRFS-MRT and FID were performed during MR-guided high-intensity focused ultrasound heating. The phase of the FIDs was used to estimate the change in angular frequency delta omega(drift) per coil element. Two correction methods were investigated: (1) using the average delta omega(drift) over all coil elements (0th-order) and (2) using coil sensitivity profiles for spatially resolved correction. Optical probes were used for independent temperature verification. In-vivo feasibility of the methods was evaluated in the leg of 1 healthy volunteer at 1.5T. Results In 30 minutes, B-0 drift led to an apparent temperature change of up to -18 degrees C and -98 degrees C at 1.5T and 3T, respectively. In the sonicated area, both corrections had a median error of 0.19 degrees C at 1.5T and -0.54 degrees C at 3T. At 1.5T, the measured median error with respect to the optical probe was -1.28 degrees C with the 0th-order correction and improved to 0.43 degrees C with the spatially resolved correction. In vivo, without correction the spatiotemporal median of the apparent temperature was at -4.3 degrees C and interquartile range (IQR) of 9.31 degrees C. The 0th-order correction had a median of 0.75 degrees C and IQR of 0.96 degrees C. The spatially resolved method had the lowest median at 0.33 degrees C and IQR of 0.80 degrees C. Conclusion FID phase information from individual receive coil elements allows spatially resolved B-0 drift correction in PRFS-based MRT.