期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 84, 期 19, 页码 12680-12685出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b02101
关键词
-
资金
- [JP26282211]
- [JP16H01162]
- [JP17H02207]
- [JP18H04426]
- [JP26882036]
- [JP16K16638]
FNC-RED exhibits innate immune receptor Toll-like receptor 4 (TLR4)/myeloid differentiation factor-2 (MD2) stimulatory activity. We have developed a divergent synthetic route to FNC-RED derivatives containing various alkyl side chains. Key features of the synthetic study include stepwise palladium catalyzed cross-coupling reactions and the construction of an all syn-cyclopentanetetrol moiety.
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