期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 85, 期 5, 页码 2918-2926出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b01833
关键词
-
资金
- National Natural Science Foundation of China [21801065, U180425, 21571052, 21601051]
Herein, we report a metal-free radical tandem C-H amination and bromination reaction with dibromohydantoin (DBH) as both the amination and bromination reagents and water as the main solvent. The reaction involves in intramolecular C-H amination and electrophilic bromination using cheap commercially available DBH. The products represent heterocyclic building blocks, readily modifiable by classical cross-coupling reactions.
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