Photoluminescence and cytotoxicity properties of new quinolinone lanthanide nano-complexes

Novel lanthanide nano-complexes of La3+, Y3+, Pr3+, Gd3+, Dy3+ and Er(3+)with quinolinone were synthesized and investigated by different fundamental tools such as C, H, N, molar conductivity, thermal, XRD and TEM analysis. In addition, FT-IR,H- 1 NMR, mass and emission spectra were used. The results introduced that ligand acting as bidentate through OO donor sites forming octahedral complexes. XRD analysis showed that all complexes are in nano-scale with amorphous and/or crystalline form. TEM analysis revealed that Pr3+ nano-complex has aggregated hybrid morphologies, on other hand Er(3+)nanocomplex has rode morphology. From fluorescence spectroscopy, Pr3+, Dy3+ and Er3+ nano-complexes are highly luminescent and their life time were detected. The antitumor activity was also recommended toward human Hepatocellular carcinoma cell line. Pr3+ nano-complex has the highest anticancer activity according to its crystal shape and nano-size. (C) 2019 Elsevier B.V. All rights reserved.