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Rosalind F. Hannen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Isoprenoid is a perfect fit for fat factor: Figure 1
Andrew J. Brown
BIOCHEMICAL JOURNAL (2011)
Lack of IL-2 in PPAR-α-deficient mice triggers allergic contact dermatitis by affecting regulatory T cells
Sandrine Dubrac et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation
Jose Augusto Nogueira-Machado et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2011)
Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities
Mayte Suarez-Farinas et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)
An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway
Gaku Tsuji et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2011)
Natural peroxisome proliferator-activated receptor-alpha agonist cream demonstrates similar therapeutic response to topical steroids in atopic dermatitis
Clarence De Belilovsky et al.
JOURNAL OF DERMATOLOGICAL TREATMENT (2011)
Modifications of the Innate Immune System in Atopic Dermatitis
Laura Maintz et al.
JOURNAL OF INNATE IMMUNITY (2011)
Caged Fluorescent Haptens Reveal the Generation of Cryptic Epitopes in Allergic Contact Dermatitis
Carl Simonsson et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2011)
ROS Quenching Potential of the Epidermal Cornified Cell Envelope
Wilbert P. Vermeij et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2011)
Characterization of the skin fungal microbiota in patients with atopic dermatitis and in healthy subjects
Enshi Zhang et al.
MICROBIOLOGY AND IMMUNOLOGY (2011)
CYP1A1 Induction in the Colon by Serum: Involvement of the PPARα Pathway and Evidence for a New Specific Human PPREα Site
Pierre-Henri Villard et al.
PLOS ONE (2011)
Activation of Aryl Hydrocarbon Receptor (AhR) Leads to Reciprocal Epigenetic Regulation of FoxP3 and IL-17 Expression and Amelioration of Experimental Colitis
Narendra P. Singh et al.
PLOS ONE (2011)
Xenobiotic Metabolism, Disposition, and Regulation by Receptors: From Biochemical Phenomenon to Predictors of Major Toxicities
Curtis J. Omiecinski et al.
TOXICOLOGICAL SCIENCES (2011)
Selective Phthalate Activation of Naturally Occurring Human Constitutive Androstane Receptor Splice Variants and the Pregnane X Receptor
Joshua G. DeKeyser et al.
TOXICOLOGICAL SCIENCES (2011)
2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation
Carrie Hayes Sutter et al.
TOXICOLOGICAL SCIENCES (2011)
Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor
Michael S. Denison et al.
TOXICOLOGICAL SCIENCES (2011)
PPAR-alpha in cutaneous inflammation
Sandrine Dubrac et al.
DERMATO-ENDOCRINOLOGY (2011)
Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema
J. M. Jungersted et al.
ALLERGY (2010)
Efficacy and Safety of Topical WBI-1001 in the Treatment of Atopic Dermatitis: Results From a Phase 2A, Randomized, Placebo-Controlled Clinical Trial
Robert Bissonnette et al.
ARCHIVES OF DERMATOLOGY (2010)
Mechanisms, regulation and consequences of protein SUMOylation
Kevin A. Wilkinson et al.
BIOCHEMICAL JOURNAL (2010)
Bioanalytical characterisation of multiple endocrine- and dioxin-like activities in sediments from reference and impacted small rivers
Said Kinani et al.
ENVIRONMENTAL POLLUTION (2010)
Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells
Jean-Marie Ramirez et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
Kupffer Cells Promote Hepatic Steatosis Via Interleukin-1β-Dependent Suppression of Peroxisome Proliferator-Activated Receptor α Activity
Rinke Stienstra et al.
HEPATOLOGY (2010)
Atopic dermatitis: the role of Langerhans cells in disease pathogenesis
Sandrine Dubrac et al.
IMMUNOLOGY AND CELL BIOLOGY (2010)
Relationship between ambient ozone concentrations and daily hospital admissions for childhood asthma/atopic dermatitis in two cities of Korea during 2004-2005
Jong-Tae Lee et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH (2010)
Murine atopic dermatitis responds to peroxisome proliferator-activated receptors alpha and beta/delta (but not gamma) and liver X receptor activators
Yutaka Hatano et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)
Modulation of T Lymphocyte Function by the Pregnane X Receptor
Sandrine Dubrac et al.
JOURNAL OF IMMUNOLOGY (2010)
Skin Cornification Proteins Provide Global Link between ROS Detoxification and Cell Migration during Wound Healing
Wilbert P. Vermeij et al.
PLOS ONE (2010)
The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole helps genes jump
Agneta Rannug
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
PPARs and Xenobiotic-Induced Adverse Effects: Relevance to Human Health
Christopher Lau et al.
PPAR RESEARCH (2010)
A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-κB family
Christoph F. A. Vogel et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Regulation of constitutive and inducible AHR signaling: Complex interactions involving the AHR repressor
Mark E. Hahn et al.
BIOCHEMICAL PHARMACOLOGY (2009)
The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxin-activated Ah receptor to cause toxic effects
Fumio Matsumura
BIOCHEMICAL PHARMACOLOGY (2009)
Abnormal skin barrier in the etiopathogenesis of atopic dermatitis
Peter M. Elias et al.
CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY (2009)
Langerhans cells are critical in the development of atopic dermatitis-like inflammation and symptoms in mice
Andreas Elentner et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses
Akihiro Kimura et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Langerhans Cell Maturation and Contact Hypersensitivity Are Impaired in Aryl Hydrocarbon Receptor-Null Mice
Bettina Jux et al.
JOURNAL OF IMMUNOLOGY (2009)
Urinary biomarker of oxidative stress in patients with psoriasis vulgaris and atopic dermatitis
K. Nakai et al.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2009)
VDR and MEK-ERK dependent induction of the antimicrobial peptide cathelicidin in keratinocytes by lithocholic acid
Mark Peric et al.
MOLECULAR IMMUNOLOGY (2009)
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells
Sara Trifari et al.
NATURE IMMUNOLOGY (2009)
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes
Niresh Hariparsad et al.
NUCLEIC ACIDS RESEARCH (2009)
The Benefits of Sunflower Oleodistillate (SOD) in Pediatric Dermatology
Lawrence F. Eichenfield et al.
PEDIATRIC DERMATOLOGY (2009)
The tangle of nuclear receptors that controls xenobiotic metabolism and transport: Crosstalk and consequences
Jean-Marc Pascussi et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2008)
Aryl hydrocarbon receptor-mediated regulation of the human estrogen and bile acid UDP-glucuronosyltransferase 1A3 gene
Tim O. Lankisch et al.
ARCHIVES OF TOXICOLOGY (2008)
Interplay of pregnane X receptor with other nuclear receptors on gene regulation
[Anonymous]
DRUG METABOLISM AND PHARMACOKINETICS (2008)
Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species
Matthew R. Milnes et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2008)
Analysis of CD25hiCD4+ regulatory T-cell subtypes in atopic dermatitis reveals a novel TH2-like population
Amanda J. Reefer et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)
Peroxisome proliferator-activated receptor α regulates skin inflammation and humoral response in atopic dermatitis
Delphine Staumont-Salle et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)
Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology
Matthias Schmuth et al.
JOURNAL OF LIPID RESEARCH (2008)
The antiapoptotic role of pregnane x receptor in human colon cancer cells
Jie Zhou et al.
MOLECULAR ENDOCRINOLOGY (2008)
Xenoreceptors CAR and PXR activation and consequences on lipid metabolism, glucose homeostasis, and inflammatory response
Amelie Moreau et al.
MOLECULAR PHARMACEUTICS (2008)
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
Francisco J. Quintana et al.
NATURE (2008)
Genetic variability of aryl hydrocarbon receptor (AhR)-mediated regulation of the human UDP glucuronosyltransferase (UGT) 1A4 gene
Thomas J. Erichsen et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2008)
Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists
Zofia Duniec-Dmuchowski et al.
BIOCHEMICAL PHARMACOLOGY (2007)
Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-κB target gene expression
Yatrik M. Shah et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Nuclear receptors in human immune cells: Expression and correlations
Andrea B. Schote et al.
MOLECULAR IMMUNOLOGY (2007)
On the role of the epidermal differentiation complex in ichthyosis vulgaris, atopic dermatitis and psoriasis
S. Hoffjan et al.
BRITISH JOURNAL OF DERMATOLOGY (2007)
Oxidative stress in the pathogenesis of skin disease
David R. Bickers et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2006)
Activation of the dioxin/aryl hydrocarbon receptor (AhR) modulates cell plasticity through a JNK-dependent mechanism
M. Diry et al.
ONCOGENE (2006)
Mutual repression between steroid and xenobiotic receptor and NF-κB signaling pathways links xenobiotic metabolism and inflammation
Changcheng Zhou et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations
Stephan Weidinger et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
Role of NF-κB in regulation of PXR-mediated gene expression -: A mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents
Xinsheng Gu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR)
MA Peraza et al.
TOXICOLOGICAL SCIENCES (2006)
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis
CNA Palmer et al.
NATURE GENETICS (2006)
Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: Liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing
Mao-Qiang Man et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2006)
Peroxisome proliferator-activated receptor alpha plays a vital role in inducing a detoxification system against plant compounds with crosstalk with other xenobiotic nuclear receptors
K Motojima et al.
FEBS JOURNAL (2006)
PPAR beta/delta selectively induces differentiation and inhibits cell proliferation
DJ Kim et al.
CELL DEATH AND DIFFERENTIATION (2006)
The dual action of ozone on the skin
G Valacchi et al.
BRITISH JOURNAL OF DERMATOLOGY (2005)
Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions
M Tauchi et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists
B Ebert et al.
CARCINOGENESIS (2005)
Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway - Direct cross-talk between phase I and II drug-metabolizing enzymes
WM Miao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion
H Masuyama et al.
MOLECULAR ENDOCRINOLOGY (2005)
Ligand-binding regulation of LXR/RXR and LXR/PPAR heterodimerizations: SPR technology-based kinetic analysis correlated with molecular dynamics simulation
LD Yue et al.
PROTEIN SCIENCE (2005)
Induction of phase I, II and III drug metabolism/transport by xenobiotics
CJ Xu et al.
ARCHIVES OF PHARMACAL RESEARCH (2005)
Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription
TG Li et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
2,3,7,8-Tetrachlorodibenzo-p-dioxin impairs differentiation of normal human epidermal keratinocytes in a skin equivalent model
A Geusau et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2005)
Role of cytochrome p4501 family members in the metabolic activation of polycyclic aromatic hydrocarbons in mouse epidermis
HE Kleiner et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2004)
Down regulation of hepatic PPARα function by AhR ligand
Z Shaban et al.
JOURNAL OF VETERINARY MEDICAL SCIENCE (2004)
Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes
CC Zhou et al.
DRUG METABOLISM AND DISPOSITION (2004)
Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR
MM Tabb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Alteration of keratinocyte differentiation and senescence by the tumor promoter dioxin
SS Ray et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2003)
Defining the role for XAP2 in stabilization of the dioxin receptor
MJ Lees et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells
PA Münzel et al.
BIOCHEMICAL PHARMACOLOGY (2003)
Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism.: I.: PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling
T Yoshikawa et al.
MOLECULAR ENDOCRINOLOGY (2003)
PPARγ and PPARδ negatively regulate specific subsets of lipopolysaccharide and IFN-γ target genes in macrophages
JS Welch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Skin lipids and epidermal differentiation in atopic dermatitis
E Proksch et al.
CLINICS IN DERMATOLOGY (2003)
Characterization of in vitro metabolites of the aryl hydrocarbon receptor ligand 6-formylindolo[3,2-b] carbazole by liquid chromatography-mass spectrometry and NMR.
L Bergander et al.
DRUG METABOLISM AND DISPOSITION (2003)
Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor
B Goodwin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism
SA Kliewer et al.
ENDOCRINE REVIEWS (2002)
Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics
A Takeshita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Linking dioxins to diabetes: Epidemiology and biologic plausibility
RBJ Remillard et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2002)
Nuclear pregnane X receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
JM Maglich et al.
MOLECULAR PHARMACOLOGY (2002)
Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis
LG Komuves et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2002)
Activators of peroxisome proliferator-activated receptors protect human skin from ultraviolet-B-light-induced inflammation
S Kippenberger et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2001)
2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation pattern of human keratinocytes in organotypic culture
JA Loertscher et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2001)
The hsp90 chaperone complex regulates intracellular localization of the dioxin receptor
A Kazlauskas et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
A Chawla et al.
NATURE MEDICINE (2001)
Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes
JM Pascussi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Peroxisome proliferator-activated receptor-α enhances lipid metabolism in a skin equivalent model
M Rivier et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2000)
Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription
K Hanley et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2000)
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