Vitamin B12 Enables Consecutive Generation of Acyl and Alkyl Radicals from One Reagent

Co complex - Cby(OMe)(7) - enables consecutive generation of alkyl and acyl radicals from adequately designed carboxylic acids possessing a halogen atom in theirs structures. Mechanistic studies reveal that alkyl corrins forms at much higher rate than the respective acyl derivatives enabling selective reactions with activated olefins.