期刊
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
卷 178, 期 -, 页码 687-704出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2019.06.010
关键词
Free radicals; Antioxidant; Reactive oxygen species
资金
- All India Council for Technical Education [AICTE], New Delhi, India
- Jamia Hamdard, New Delhi, India
Free radicals generated due to exposure of radiation, environmental pollutants and as by-products of metabolised drugs. These free radicals are antagonized by molecules which are antioxidant in nature. Antioxidants are the substances which inhibit oxidation. They are moreover acknowledged as free radical scavengers as they form minor reactive species via radicals. Based on origin, they are categorised into two types: exogenous and endogenous antioxidants. An Antioxidant reduces the occurrence of different disorders like: aging, cancer, diabetes, inflammation, liver disease, cardiovascular disease, cataract and nephrotoxicity and neurodegenerative disorders. Dietary antioxidants are thought to have potential capacities to avert oxidative anxiety induced diseases. This review figures the various researches on pharmacological activity of natural along with synthetic antioxidant molecules. (C) 2019 Elsevier Masson SAS. All rights reserved.
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