期刊
CURRENT OPINION IN GENETICS & DEVELOPMENT
卷 57, 期 -, 页码 16-24出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2019.06.004
关键词
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资金
- Medical Research Council [MR/S007792/1]
- Biotechnology and Biological Sciences Research Council [M008517]
- Wellcome Trust [102489/Z/13/Z]
- BBSRC [BB/R00627X/1] Funding Source: UKRI
- MRC [MR/S007792/1] Funding Source: UKRI
- Wellcome Trust [102489/Z/13/Z] Funding Source: Wellcome Trust
Neural crest cells are a multipotent embryonic stem cell population that migrate large distances to contribute a variety of tissues. The cranial neural crest, which contribute to tissues of the face and skull, undergo collective migration whose movement has been likened to cancer metastasis. Over the last few years, a variety of mechanisms for the guidance of collective cranial neural crest cell migration have been described: mostly chemical, but more recently mechanical. Here we review these different mechanisms and attempt to integrate them to provide a unified model of collective cranial neural crest cell migration.
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