期刊
CHEMISTRY-AN ASIAN JOURNAL
卷 14, 期 24, 页码 4688-4695出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/asia.201900960
关键词
5-endo-dig Cyclization; Domino reactions; Heterocycles; Indolizine; Triarylmethanes
资金
- IISER Mohali
- UGC, New Delhi
A sequential two-step method for the synthesis of hetero-arylated triarylmethanes through a Ag-catalyzed sequential double cyclization-nucleophilic addition cascade is described. This methodology basically involves an initial 5-endo-dig cyclization of o-alkynyl anilines to provide 2-substituted indole derivatives, which then react with 2-(2-enynyl)-pyridines to afford indolizine-containing unsymmetrical triarylmethanes through another 5-endo-dig cyclization.
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