期刊
CEREBROVASCULAR DISEASES
卷 48, 期 1-2, 页码 26-31出版社
KARGER
DOI: 10.1159/000502450
关键词
Optical coherence tomography; Cerebral aneurysms; Cerebral vessel walls; Intraoperative imaging; Vascular neurosurgery
资金
- OptoMedical Technologies GmbH
Objective: The present study was conducted to explore the value of 3-dimensional microscope integrated extravascular optical coherence tomography (OCT) as the first suitable intraoperative imaging modality of cerebral aneurysm (CA) and parent vessel wall morphology. Methods: Incidental CAs (n = 16) of the anterior circulation with indication for microsurgical clipping were scanned. Results: Analysis revealed that intraoperative OCT achieved to delineate the microstructural composition of the parent vessel in all cases and the CA wall in 68.8%. Clinical relevant characteristics such as thickness, calcification, residual tunica media, and atherosclerotic plaque of CA wall could be demonstrated with high image quality approaching the spatial resolution of histopathology. Conclusion: Our findings demonstrate that intraoperative OCT may hold promise as an additional imaging tool during neurovascular procedures.
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