相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Novel application of metformin combined with targeted drugs on anticancer treatment
Jun Deng et al.
CANCER SCIENCE (2019)
Attenuation of TGFBR2 expression and tumour progression in prostate cancer involve diverse hypoxia-regulated pathways
Hui Zhou et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Phenformin alone or combined with gefitinib inhibits bladder cancer via AMPK and EGFR pathways
Yanjun Huang et al.
CANCER COMMUNICATIONS (2018)
Metformin suppresses triple-negative breast cancer stem cells by targeting KLF5 for degradation
Peiguo Shi et al.
CELL DISCOVERY (2017)
Concomitant underexpression of TGFBR2 and overexpression of hTERT are associated with poor prognosis in cervical cancer
Hui Yang et al.
SCIENTIFIC REPORTS (2017)
Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production
Angela Mogavero et al.
SCIENTIFIC REPORTS (2017)
Metformin impairs systemic bile acid homeostasis through regulating SIRT1 protein levels
Qi Chen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2017)
Myeloid-specific TGF-β signaling in bone promotes basic-FGF and breast cancer bone metastasis
X. Meng et al.
ONCOGENE (2016)
Synergistic therapeutic effects of Schiffs base cross-linked injectable hydrogels for local co-delivery of metformin and 5-fluorouracil in a mouse colon carcinoma model
Xilong Wu et al.
BIOMATERIALS (2016)
Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma
Koji Harada et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
ZNF32 contributes to the induction of multidrug resistance by regulating TGF-β receptor 2 signaling in lung adenocarcinoma
Jun Li et al.
CELL DEATH & DISEASE (2016)
Dual targeting of ANGPT1 and TGFBR2 genes by miR-204 controls angiogenesis in breast cancer
Ali Flores-Perez et al.
SCIENTIFIC REPORTS (2016)
Metformin induces degradation of mTOR protein in breast cancer cells
Mohamed Alalem et al.
CANCER MEDICINE (2016)
Metformin is a novel suppressor for transforming growth factor (TGF)-β1
Han Xiao et al.
SCIENTIFIC REPORTS (2016)
Metformin and gefitinib cooperate to inhibit bladder cancer growth via both AMPK and EGFR pathways joining at Akt and Erk
Mei Peng et al.
SCIENTIFIC REPORTS (2016)
Colorectal Cancer Classification and Cell Heterogeneity: A Systems Oncology Approach
Moises Blanco-Calvo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Targeting the TGFβ pathway for cancer therapy
Cindy Neuzillet et al.
PHARMACOLOGY & THERAPEUTICS (2015)
TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer
S. Busch et al.
ONCOGENE (2015)
Prognostic implication of the loss of TGFBR2 expression in oral carcinoma
V. P. Sivadas et al.
NEOPLASMA (2015)
Metformin Sensitizes EGFR-TKI-Resistant Human Lung Cancer Cells In Vitro and In Vivo through Inhibition of IL-6 Signaling and EMT Reversal
Li Li et al.
CLINICAL CANCER RESEARCH (2014)
Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer
Soichiro Honjo et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
MicroRNA-301a promotes migration and invasion by targeting TGFBR2 in human colorectal cancer
Wenpeng Zhang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2014)
Repurposing to Fight Cancer: The Metformin-Prostate Cancer Connection
Anna Azvolinsky
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2014)
Metformin reverses multidrug resistance and epithelial-mesenchymal transition (EMT) via activating AMP-activated protein kinase (AMPK) in human breast cancer cells
Chen Qu et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2014)
Metformin Induces Apoptosis and Cell Cycle Arrest Mediated by Oxidative Stress, AMPK and FOXO3a in MCF-7 Breast Cancer Cells
Eveline A. I. F. Queiroz et al.
PLOS ONE (2014)
Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
Andreas Janzer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Growth inhibition of colon cancer cells by compounds affecting AMPK activity
Michael A. Lea et al.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY (2014)
LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin
David B. Shackelford et al.
CANCER CELL (2013)
Association of metformin use with cancer incidence and mortality: A meta-analysis
Pengpeng Zhang et al.
CANCER EPIDEMIOLOGY (2013)
Metformin targets c-MYC oncogene to prevent prostate cancer
Tunde Akinyeke et al.
CARCINOGENESIS (2013)
Improving outcomes in colorectal cancer: Where do we go from here?
Eric Van Cutsem et al.
EUROPEAN JOURNAL OF CANCER (2013)
The roles of TGFβ in the tumour microenvironment
Michael Pickup et al.
NATURE REVIEWS CANCER (2013)
TGF-beta signalling in colon carcinogenesis
Pavlos Lampropoulos et al.
CANCER LETTERS (2012)
Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers
Xin-Sheng Deng et al.
CELL CYCLE (2012)
STAT3 Is Necessary for Proliferation and Survival in Colon Cancer-Initiating Cells
Li Lin et al.
CANCER RESEARCH (2011)
Induction of apoptosis by metformin in epithelial ovarian cancer: Involvement of the Bcl-2 family proteins
Amber Yasmeen et al.
GYNECOLOGIC ONCOLOGY (2011)
Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
Heather A. Hirsch et al.
CANCER RESEARCH (2009)
The basics of epithelial-mesenchymal transition
Raghu Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
The Effects of Adiponectin and Metformin on Prostate and Colon Neoplasia Involve Activation of AMP-Activated Protein Kinase
Mahvash Zakikhani et al.
CANCER PREVENTION RESEARCH (2008)
Prostate tumor progression is mediated by a paracrine TGF-β/Wnt3a signaling axis
X. Li et al.
ONCOGENE (2008)
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
Monica Buzzai et al.
CANCER RESEARCH (2007)
Regulation of Metastases by signal transducer and activator of transcription 3 signaling pathway: Clinical implications
Suyun Huang
CLINICAL CANCER RESEARCH (2007)
Prognostic significance of transforming growth factor β receptor II in estrogen receptor-negative breast cancer patients
MB Buck et al.
CLINICAL CANCER RESEARCH (2004)
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
PM Siegel et al.
NATURE REVIEWS CANCER (2003)