期刊
BRITISH JOURNAL OF SURGERY
卷 106, 期 11, 页码 1488-1494出版社
WILEY
DOI: 10.1002/bjs.11299
关键词
-
类别
资金
- Dutch Cancer Society [2013-6486]
Background Determinants of the use of breast MRI in patients with ductal carcinoma in situ (DCIS) in the Netherlands were studied, and whether using MRI influenced the rates of positive resection margins and mastectomies. Methods All women aged less than 75 years, and diagnosed with DCIS between 2011 and 2015, were identified from the Netherlands Cancer Registry. Multivariable logistic regression analyses were performed, adjusting for incidence year, age, hospital type, DCIS grade and multifocality. Results Breast MRI was performed in 2382 of 10 415 DCIS cases (22 center dot 9 per cent). In multivariable analysis, patients aged less than 50 years, those with high- or intermediate-grade DCIS and patients with multifocal disease were significantly more likely to have preoperative MRI. Patients undergoing MRI were more likely to have a mastectomy, either as first surgical treatment or following breast-conserving surgery (BCS) in the event of positive margins (odds ratio (OR) 2 center dot 11, 95 per cent c.i. 1 center dot 91 to 2 center dot 33). The risk of positive surgical margins after BCS was similar for those with versus without MRI. The secondary mastectomy rate after BCS was higher in patients who had MRI, especially in women aged less than 50 years (OR 1 center dot 94, 1 center dot 31 to 2 center dot 89). All findings were similar for low- and intermediate/high-grade DCIS. Conclusion Adding MRI to conventional breast imaging did not improve surgical outcome in patients diagnosed with primary DCIS. The likelihood of undergoing a mastectomy was twice as high in the MRI group, and no reduction in the risk of margin involvement was observed after BCS.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据