4.1 Article

Primary sellar melanocytoma: report of two cases treated at the same institution and their long-term outcome

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BRITISH JOURNAL OF NEUROSURGERY
卷 37, 期 4, 页码 803-807

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TAYLOR & FRANCIS LTD
DOI: 10.1080/02688697.2019.1667485

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Sellar melanocytoma; pituitary tumor; transsphenoidal surgery; primary melanocytic brain tumors; leptomeningeal melanocytes

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Sellar melanocytomas are benign, slow-growing tumors with a high risk of recurrence. This study reported two cases treated at the same institute, with one undergoing gross total resection and the other undergoing subtotal resection followed by gamma knife radiosurgery.
Sellar melanocytomas represent a small subgroup of primary melanocytic tumors arising from leptomeningeal melanocytes. They are benign, slow-growing tumors with a high risk of recurrence. We report two cases of sellar melanocytoma treated at the same institute. A 35-year-old woman presented with amenorrhea and an intrasellar mass with suprasellar extension simulating a hemorrhagic pituitary adenoma. The second case is a 51-year-old man with progressive visual loss and a recurrence of primary sellar and suprasellar melanocytoma. The first patient underwent gross total resection and the second patient underwent subtotal resection. Neither of them was treated with postoperative adjuvant therapies. The second patient had tumor regrowth 75 months after surgery; he therefore underwent gamma knife radiosurgery. Both patients are alive and well at the last follow-up (140 and 93 months, respectively).

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