期刊
BRAIN STRUCTURE & FUNCTION
卷 224, 期 9, 页码 3001-3018出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00429-019-01945-2
关键词
Cingulate cortex; Limbic systems; Hippocampus; Orbitofrontal cortex; Emotion; Memory; Depression
Evidence is provided for a new conceptualization of the connectivity and functions of the cingulate cortex in emotion, action, and memory. The anterior cingulate cortex receives information from the orbitofrontal cortex about reward and non-reward outcomes. The posterior cingulate cortex receives spatial and action-related information from parietal cortical areas. It is argued that these inputs allow the cingulate cortex to perform action-outcome learning, with outputs from the midcingulate motor area to premotor areas. In addition, because the anterior cingulate cortex connects rewards to actions, it is involved in emotion; and because the posterior cingulate cortex has outputs to the hippocampal system, it is involved in memory. These apparently multiple different functions of the cingulate cortex are related to the place of this proisocortical limbic region in brain connectivity.
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