期刊
BIOMEDICINE & PHARMACOTHERAPY
卷 116, 期 -, 页码 -出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2019.108999
关键词
Condensed tannin; Bio-active compound; Antioxidant capacity; Anticancer; Antidiabetic; Cardiovascular disease
资金
- Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences [CAMS-2017-12M-1-011]
- National Drug Innovation Major Project [2018ZX09711-001-005]
Proanthocyanidins are condensed tannins with various pharmacological properties. These phytochemicals are considered as 'offense and defense molecules because of their human health benefits. The validation of their diverse health aspects, namely, antioxidant, anticancer, antidiabetic, neuroprotective, and antimicrobial has earned them repute in thermochemistry. Proanthocyanidins are oligo- or polymers of monomeric flavan-3-ols produced as an end product of flavonoid biosynthetic pathway. Agricultural wastes and food processing wastes contain immense amount of proanthocyanidins, exploitation of which can be a sustainable source of dietary supplements and functional ingredients. The current review article discusses recent developments in the health promoting properties of proanthocyanidins and the associated hurdles.
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